Knowledge Tree
bioactive compounds
Also known as: bioactive constituents, bioactive phytochemicals, bioactive molecules
Facts (90)
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Medicinal plants and human health: a comprehensive review of ... link.springer.com Nov 5, 2025 18 facts
referenceMulti-omics integration, which combines genomics, transcriptomics, proteomics, and metabolomics data, provides a comprehensive understanding of plant biology and reveals how genetic information flows to produce phenotypes, including the synthesis of bioactive compounds.
claimMedicinal plants serve as a vital source of structurally diverse bioactive compounds that possess broad therapeutic potential.
claimAqueous extracts from various medicinal plant families demonstrate in vitro inhibitory activity against viral pathogens, including herpes simplex virus and influenza virus, due to bioactive compounds that disrupt viral replication cycles.
claimMetabolomics focuses on identifying, quantifying, and characterizing metabolites with molecular weights below 1000 daltons, which include most bioactive compounds responsible for therapeutic effects.
referenceMoses RJ, Edo GI, Jikah AN, and Agbo JJ published a 2024 study on the bioactive compounds and biological activities of garlic.
claimContemporary research initiatives are validating traditional therapeutic approaches by identifying bioactive compounds within medicinal plants that demonstrate significant therapeutic potential, which has led to the development of new pharmaceutical agents and treatment protocols.
claimThe predominant compounds within essential oils differ among plant species, with each species possessing distinct combinations of bioactive molecules that enhance therapeutic efficacy, according to Monib (2024).
claimWild-harvesting methods for medicinal plants have led to severe conservation concerns, with an estimated 4,000 to 10,000 species at risk of extinction due to overexploitation, especially when bioactive compounds are concentrated in roots, bark, and underground storage organs.
referenceSingh, Patle, and Kumar (2024) developed microwave- and ultrasonication-based intensified and synergetic approaches for the extraction of bioactive compounds from pomegranate peels, including parametric and kinetic studies.
claimThe implementation of multi-omics strategies has established a systems biology paradigm that synthesizes genomic, transcriptomic, proteomic, and metabolomic datasets to reveal regulatory hierarchies controlling the production of bioactive compounds in plants.
referenceTanasa et al. (2025) reviewed the bioactive compounds found in vegetal organs of Taraxacum species (Dandelion) and their biomedical applications.
referenceLiu et al. (2022) provide a review of Elderberry (Sambucus nigra L.), covering its bioactive compounds, health functions, and applications.
referenceA. Choudhury (2022) discusses the potential role of bioactive phytochemicals in combination therapies for antimicrobial activity in the Journal of Pharmacopuncture.
claimMedicinal plants contain primary and secondary metabolites categorized as bioactive compounds, including alkaloids, steroids, tannins, phenolic compounds, and flavonoids, which can elicit physiological effects on the human body.
claimSpecialized databases catalog thousands of plant metabolites, creating valuable resources for identifying bioactive compounds and understanding their biological functions.
referenceThis review aims to explain how interdisciplinary methods—specifically the combination of omics technologies, AI, and nanotechnology—improve the understanding of plant biosynthetic pathways, accelerate the discovery and characterization of bioactive compounds, and enhance treatment effectiveness while addressing quality control, contamination, and regulatory standardization.
claimOmics platforms, including genomics, metabolomics, proteomics, and spatial omics, enable the mapping of biosynthetic pathways, regulatory networks, and spatial chemical distributions to accelerate the discovery and characterization of bioactive compounds in medicinal plants.
referenceThe article titled 'Medicinal plants and human health: a comprehensive review of bioactive compounds, therapeutic effects, and applications' was authored by R. Latif and T. Nawaz and published in the journal Phytochem Rev in 2026, volume 25, pages 2299–2342 (DOI: 10.1007/s11101-025-10194-7).
Medicinal plants: bioactive compounds, biological activities ... frontiersin.org 8 facts
referenceResurrection plants serve as a source of natural bioactive compounds, transitioning from traditional use to scientifically validated sustainable applications, according to a 2024 study in Metabolites.
claimUtilizing an ethnopharmacological strategy for the screening of bioactive components provides multiple advantages, including the facilitation of pre-screening gathered plant species based on ethnomedicinal applications and preliminary safety standards, which reduces the time and cost of the process.
procedureThe indiscriminate method of plant collection involves gathering plants from several regions to generate a large quantity of samples, which ensures chemical diversity and increases the likelihood of discovering biologically active components.
claimBioactive compounds in medicinal plant extracts can improve the effectiveness of current antibiotics and help prevent the development of antibiotic resistance.
claimAdvanced methodologies such as genomics, proteomics, and metabolomics help expedite the identification and characterization of bioactive compounds in medicinal plants for the development of new antibiotics.
claimThe ethnopharmacological approach involves selecting plant species based on the preferences of specific demographic groups for treating infectious diseases like diarrhea and malaria, which has proven effective for identifying bioactive compounds for anti-infective pharmaceuticals.
claimBioactive compounds in medicinal plant extracts can cause bacterial lysis by interacting with bacterial membrane components like anionic phospholipids and lipopolysaccharides, leading to membrane disruption.
referenceVaou et al. (2022) published a study in the journal Antibiotics regarding the interactions between medical plant-derived bioactive compounds, specifically focusing on antimicrobial combination effects.
Wild edible plants for food security, dietary diversity, and nutraceuticals frontiersin.org Nov 27, 2025 7 facts
claimBioactive compounds in wild edible plants include short peptides, polyphenols, phytosterols, carotenoids, vitamins, short-chain fatty acids, terpenoids, and polysaccharides, which vary in structural groups, functions, distribution, and bioavailability, according to Galanakis (2017).
referenceShahar et al. (2023) analyzed the nutritional composition, antioxidant activity, and bioactive compounds of Thymus serpyllum L., identifying it as an underexploited wild aromatic plant.
claimBioactive compounds found in wild edible plants exhibit effects including anti-inflammatory, antimicrobial, antioxidant, antidiabetic, anti-depressant, cholesterol reduction, memory enhancement, and immune modulation.
referenceKolniak-Ostek et al. (2020) characterized the bioactive compounds found in the seeds of Opuntia ficus-indica (L.) Mill. from Spanish cultivars, published in Molecules.
referenceBahukhandi et al. (2023) documented the bioactive compounds, uses, and nutraceutical potential of Fragaria species (specifically Fragaria indica and Fragaria nubicola) in a chapter on Himalayan fruits and berries.
referenceTomšik et al. (2016) optimized the ultrasound-assisted extraction process for bioactive compounds from wild garlic (Allium ursinum L.).
referenceDasila and Singh (2022) documented the bioactive compounds and biological activities of Elaeagnus latifolia L., which is an underutilized fruit found in the north-east Himalaya region of India.
Pharmacological Uses of New Bioactive Compounds from Medicinal ... ouci.dntb.gov.ua 6 facts
referenceDar, Shahnawaz, Ahanger, and Majid (2023) authored a review exploring diverse bioactive compounds derived from medicinal plants.
referenceEl-Saadony et al. (2025) published a comprehensive review in Frontiers in Immunology regarding medicinal plants, focusing on their bioactive compounds, biological activities, ability to combat multidrug-resistant microorganisms, and benefits to human health.
referenceAcharya, C.K., Khan, N.K., & Madhu, N.R. conducted a comparative GC-MS analysis of bioactive compounds in the ethyl acetate fruit extract of Phyllanthus emblica L. (Gaertn.) from two phyto-geographically contrasting regions of West Bengal, India, published in the Journal of Plant Science Research in 2022.
referenceTran, Pham, and Le (2020) reviewed bioactive compounds in anti-diabetic plants and their transition from herbal medicine to modern drug discovery in the journal Biology.
referenceAdeleye, O. A., et al. published a study in 2021 titled 'Medicinal Plants with Potential Inhibitory Bioactive Compounds against Coronaviruses' in the Advanced Pharmaceutical Bulletin.
claimProminent bioactive compounds found in medicinal plants include flavonoids, tannins, phenolic acids, terpenoids, alkaloids, coumarins, essential oils, and polypeptides.
Advances in Pharmacognosy for Modern Drug Discovery and ... jbph.org 6 facts
referenceThe article 'Natural product-inspired strategies towards the discovery of novel bioactive molecules' was published in the Future Journal of Pharmaceutical Sciences in 2024, volume 10, issue 1, article 55.
referenceSasidharan S, Chen Y, Saravanan D, Sundram KM, and Latha LY published a study in the African Journal of Traditional, Complementary and Alternative Medicines in 2011 detailing methods for the extraction, isolation, and characterization of bioactive compounds from plant extracts.
claimChristian OE, Perry DA, Telchy AI, Walton PN, and Williams D identified bioactive compounds isolated from a marine sponge that selectively inhibit Neisseria gonorrhoeae, as published in Antibiotics in 2024.
claimEsposito R, Federico S, Bertolino M, Zupo V, Costantini M. published a review in Marine Drugs (2022) characterizing Marine Demospongiae as a source of bioactive compounds.
referenceKarthikeyan A, Joseph A, and Nair BG published 'Promising bioactive compounds from the marine environment and their potential effects on various diseases' in the Journal of Genetic Engineering and Biotechnology in 2022.
claimMetabolomics is applied in pharmacognosy to facilitate the discovery of new bioactive compounds, as discussed by Wolfender et al. in 2019.
Pharmacological Uses of New Bioactive Compounds from Medicinal ... academia.edu 6 facts
referenceDincheva, Badjakov, and Galunska (2023) published research on bioactive compounds derived from plants, specifically examining their potential applications in nutraceutical and pharmaceutical fields.
referenceThe review article 'Medicinal plants: bioactive compounds, biological activities, combating multidrug-resistant microorganisms, and human health benefits' was published in Frontiers in Immunology in 2025.
referenceAtanasov et al. (2015) published a review in Biotechnology Advances titled 'Discovery and resupply of pharmacologically active plant-derived natural products,' which discusses the processes involved in identifying and obtaining bioactive compounds from plants.
referenceS. N. Jiménez-García et al. published a 2013 article in the Polish Journal of Food and Nutrition Sciences discussing approaches for enhancing the expression of secondary metabolites as bioactive compounds in plants for agronomic and human health purposes.
referenceBioactive compounds found in anti-diabetic plants are a subject of modern drug discovery research, transitioning from traditional herbal medicine.
referenceDar et al. (2023) published a review in The Journal of Phytopharmacology exploring diverse bioactive compounds derived from medicinal plants.
Investigation of nutritional and phytochemical properties of wild ... nature.com Dec 9, 2025 5 facts
claimSecondary phytochemical screening identifies bioactive compounds such as alkaloids, flavonoids, phenols, saponins, and tannins, which are responsible for the therapeutic efficacy of plants.
claimThe medicinal plants studied in the Renukaji Wildlife Sanctuary contain bioactive compounds including saponins, alkaloids, and flavonoids, as well as essential minerals including Na, N, K, P, Zn, Fe, Cu, Mn, Ca, Mg, and S.
claimScientific profiling of essential minerals, nutrients, and bioactive compounds in medicinal plants supports the safe use of these plants and aids in the development of standardized herbal formulations.
claimPhytoconstituents are bioactive compounds found in vegetation, such as flavonoids, alkaloids, and saponins, that possess medicinal properties and contribute to therapeutic effects.
procedurePhytochemical analysis involves identifying bioactive compounds in plant materials by subjecting dried and powdered samples to solvent extraction using solvents such as methanol, ethanol, or acetone, followed by filtration, concentration, and standard chemical testing.
Ethnobotanical study of food plants used in traditional medicine in ... link.springer.com Nov 26, 2025 5 facts
claimScientific literature recognizes ginger (Zingiber officinale) as an effective phytotherapeutic agent for gastrointestinal disorders and respiratory symptoms due to its bioactive compounds with anti-inflammatory, antioxidant, and antimicrobial properties.
claimChakraborty et al. (2022) identified Allium cepa (onion) as a source of bioactive phytochemicals with potential health benefits.
claimPrevious studies have identified decoction as the optimal method for extracting the maximum concentration of bioactive constituents from plants.
referenceKincses et al. (2018) identified bioactive compounds from the African medicinal plant Cleistochlamys kirkii that act as resistance modifiers in bacteria.
referenceMao et al. (2019) documented the bioactive compounds and bioactivities of ginger (Zingiber officinale Roscoe).
Nutraceutical Compounds of edible wild plants collected in Central ... wildlife-biodiversity.com Sep 26, 2024 4 facts
claimThe authors suggest that the consumption of the studied edible wild plants could provide significant health benefits due to their content of nutrients and biologically active components.
referenceSánchez-Mata et al. (2012) published a study in Genetic Resources and Crop Evolution (59(3), 431–443) identifying wild vegetables of the Mediterranean area as valuable sources of bioactive compounds.
claimThe study evaluated the nutritional value, biologically active components, and total antioxidant capacity (ORAC) of nine edible wild plant species found in Central Italy: Allium neapolitanum Cirillo, Allium triquetrum L., Foeniculum vulgare Mill., Melissa officinalis L., Thymus serpyllum L., Sonchus oleraceus L., Reichardia picroides L. Roth, Rhagadiolus stellatus L. Gaertn, and Plantago coronopus L.
referenceMaurizi et al. (2015) characterized the bioactive compounds and antioxidant properties of three edible wild plants traditionally consumed in the Umbria Region of Central Italy: Bunias erucago L. (corn rocket), Lactuca perennis L. (mountain lettuce), and Papaver rhoeas L. (poppy).
A Comprehensive Review on the Therapeutic Properties of ... traditionalmedicine.actabotanica.org 4 facts
claimAloe vera (Aloe barbadensis) is a succulent plant containing a gel rich in vitamins, minerals, and bioactive compounds.
claimMany bioactive compounds present in medicinal plants exhibit poor solubility, low absorption, and rapid metabolism, which leads to reduced therapeutic efficacy.
claimCollaboration between traditional healers, local communities, and scientific researchers can facilitate knowledge exchange, enabling the identification of new bioactive compounds, validation of traditional uses, and development of evidence-based practices.
claimGinger (Zingiber officinale) is a spice containing bioactive compounds, including gingerol, which is responsible for its therapeutic effects.
Medicinal Plants and Traditional Uses and Modern Applications jneonatalsurg.com Mar 17, 2025 3 facts
referenceAhmad, I., & Mehmood, Z. (2017) published research regarding the bioactive compounds of medicinal plants and their uses in traditional medicine.
referenceGhosh and Ray (2020) published an overview titled 'Phytochemicals and bioactive compounds from medicinal plants: An overview' in Medicinal Chemistry Research.
claimModern pharmacological research is currently exploring and validating the therapeutic potential of medicinal plants by identifying bioactive compounds that contribute to their medicinal effects.
Phytochemical and Pharmacological Studies of Traditionally Used ... heraldopenaccess.us 3 facts
claimThe application of extracted bioactive components from herbs in the formulation of functional foods and nutraceuticals is gaining popularity due to changing consumer lifestyles.
claimHerbal medicines contain more bioactive components and possess health benefits superior to those provided by chemically synthesized drugs.
claimMousavi, MohdSalleh, and Murugaiyah (2018) identified phytochemical and bioactive compounds in the methanol extract and fractions of Ocimum tenuiflorum leaves, noting its anti-diabetic potential.
Ethnobotanical and Food Composition Monographs of Selected ... ouci.dntb.gov.ua 2 facts
referenceRuiz-Rodríguez et al. (2014b) determined that wild Arbutus unedo L. and Rubus ulmifolius Schott fruits are underutilized sources of bioactive compounds with antioxidant capacity.
referenceRuiz-Rodríguez BM (2014) completed a PhD thesis at the Universidad Complutense de Madrid evaluating the nutritional value, bioactive compounds, and antioxidant capacity of wild fruits traditionally used in human diets.
Investigation Utilization of Medicinal Plants: From Historical ... sciltp.com 2 facts
claimVeiga Junior, V.F. and Pinto, A.C. identified Brazilian biodiversity as a rich source of bioactive compounds.
referenceGhosh, Mandi, and Jha published 'Plant biotechnology for production of bioactive compounds: Progress and future prospects' in Biotechnology Advances in 2021, volume 50, article 107769.
Traditional Uses, Bioactive Compounds, and Pharmacological ... pmc.ncbi.nlm.nih.gov 1 fact
claimBioactive compounds in medicinal plants exhibit antimicrobial, anticancer, antidiabetic, anti-inflammatory, and antioxidant effects.
Medicinal plants meet modern biodiversity science | Request PDF researchgate.net Mar 3, 2026 1 fact
claimMedicinal plants serve as a significant source of bioactive compounds that are essential for applications in the pharmaceutical, cosmetic, and nutraceutical industries.
Vernonia amygdalina: a comprehensive review of the ... frontiersin.org 1 fact
claimOlusola-Makinde O., Olabanji O. B., and Ibisanmi T. A. (2021) evaluated the bioactive compounds of Vernonia amygdalina Delile extracts and their antibacterial effects on water-related bacteria.
Medicinal Plants with Potential Inhibitory Bioactive Compounds ... pmc.ncbi.nlm.nih.gov 1 fact
claimThe review titled 'Medicinal Plants with Potential Inhibitory Bioactive Compounds' identified twenty medicinal plants containing bioactive compounds that demonstrate potential inhibitory activity against coronaviruses.
Treatment of Infectious Diseases with Bioactive Compounds from ... frontiersin.org 1 fact
claimThe use of bioactive compounds and derivatives from medicinal plants is a promising strategy for treating the current upsurge in infectious diseases.
Bioactivity of Medicinal Plants and Extracts | MDPI Books mdpi.com 1 fact
referenceThe MDPI book titled "Bioactivity of Medicinal Plants and Extracts" contains a collection of original research and review articles focused on new advances in the development and application of bioactive compounds.
Review article Medicinal importance, pharmacological activities, and ... sciencedirect.com 1 fact
claimPlants develop different bioactive molecules.
Unraveling Nature's Pharmacy: Transforming Medicinal Plants into ... pmc.ncbi.nlm.nih.gov 1 fact
claimThe ethnopharmacological applications of plants have served as a crucial source of leading bioactive compounds during the initial phases of drug discovery.
New Insights in the Research on Bioactive Compounds from Plant ... mdpi.com Feb 7, 2025 1 fact
claimThe exploration of bioactive compounds derived from plants has become a cornerstone of innovation in the nutraceutical and pharmaceutical sectors.
Bioactive Compounds Derived from Plants and Their Medicinal ... pmc.ncbi.nlm.nih.gov Nov 14, 2025 1 fact
claimThe collection of studies published in 'Bioactive Compounds Derived from Plants and Their Medicinal ...' consists of 17 individual studies.
Exploring the Diverse Bioactive Compounds from Medicinal Plants researchgate.net 1 fact
claimThe review titled 'Exploring the Diverse Bioactive Compounds from Medicinal Plants' aims to explore the diverse range of medicinal plant bioactive substances and their pharmacological activities.