concept

alkaloids

Facts (61)

Sources
Medicinal plants: bioactive compounds, biological activities ... frontiersin.org Frontiers in Immunology 12 facts
claimBecause natural sources typically yield minimal quantities of alkaloids, it is essential to devise alternate extraction procedures to obtain pure alkaloids.
claimThe chemotaxonomic method for selecting medicinal plants relies on the presence of specific chemotaxonomic markers within a plant family or genus, which involves phytochemical screening to detect active biological markers such as flavonoids and alkaloids.
claimBioactive chemicals in medicinal plants, such as terpenoids, flavonoids, and alkaloids, engage with microbial cell membranes to cause structural impairment.
claimAlkaloids are significant in treating multidrug-resistant (MDR) infectious diseases due to their antibacterial capabilities, leading to increased scientific focus on these secondary plant metabolites.
claimMedicinal plants contain a complex array of bioactive chemicals, including alkaloids, terpenoids, flavonoids, and phenolics, which create a 'cocktail' effect that challenges bacteria attempting to acquire resistance.
measurementResearchers have identified various alkaloids including strychnine, emetine, brucine, piperine, caffeine, quinine, cinchonine, and colchicine, with over 10,000 alkaloids recorded to date.
claimMedicinal plants contain diverse bioactive chemicals including coumarins, flavonoids, phenolics, alkaloids, terpenoids, tannins, essential oils, lectins, polypeptides, and polyacetylenes.
claimAlkaloids, bioactive compounds found in Dicranostigma leptopodum (eastern horned poppies), are effective against the MDR microorganism Klebsiella pneumoniae.
claimAlkaloids exhibit significant biological activity because their nitrogen atoms (which absorb protons) and amine hydrogen atoms (which contribute protons) allow them to establish hydrogen bonds with enzymes, receptors, and proteins.
claimAlkaloids, including ellagic and tannic acids, along with various flavonoids, impede efflux pump activity in bacteria such as Acinetobacter baumannii.
claimAlkaloids and phenolic acids attach to the active sites of DNA gyrase, topoisomerase, and β-lactamase, hindering microbial DNA replication and cellular division.
claimAlkaloids are nitrogen-containing secondary metabolites found in many plants that comprise organic acids, exhibit hemolytic activity, and are toxic to bacteria.
Medicinal plants and human health: a comprehensive review of ... link.springer.com Springer Nov 5, 2025 10 facts
claimDonepezil is a synthetic drug that was first derived from natural alkaloids and remains a standard therapeutic option.
claimThe mechanism of cholinesterase inhibition by alkaloids involves reversible attachment to the enzyme's active region, which inhibits acetylcholine breakdown and extends neurotransmitter availability.
claimAlkaloids derived from Neem (Azadirachta indica) obstruct bacterial protein synthesis and cellular metabolism.
claimEveryday foods including gluten-containing grains, fruits, legumes, and vegetables contain compounds such as gliadin, cyanogenic glycosides, alkaloids, and lectins that may provoke allergic or adverse reactions in some individuals.
referenceAlkaloids and lectins are classified as plant toxins, as detailed in the 2024 book 'Natural poisons and venoms: plant toxins: alkaloids and lectins' by Teuscher and Lindequist.
claimAlkaloids, such as berberine and camptothecin, restore the function of the p53 tumor suppressor protein in mutant cancer cells.
claimAlkaloids from the flowering plant used by traditional healers in Madagascar have revolutionized childhood leukemia treatment and transformed Hodgkin’s lymphoma from a fatal diagnosis to a largely curable condition.
claimAlkaloids including galantamine from snowdrops (Galanthus species), rivastigmine from Calabar bean, and huperzine A from Chinese club moss (Huperzia serrata) inhibit acetylcholinesterase and butyrylcholinesterase.
claimPhytochemicals, including alkaloids, phenolic compounds, terpenoids, and sulfur-containing molecules, demonstrate significant pharmacological capabilities that have placed them at the forefront of modern drug development and therapeutic innovation.
claimMedicinal plants contain primary and secondary metabolites categorized as bioactive compounds, including alkaloids, steroids, tannins, phenolic compounds, and flavonoids, which can elicit physiological effects on the human body.
Vernonia amygdalina: a comprehensive review of the ... frontiersin.org Frontiers 10 facts
measurementVernonia amygdalina contains 305 mg/g of flavonoids, 104 mg/g of phytate, 6 mg/g of saponin, 1.7 mg/mL of tannin, and 20 mg/mL of alkaloids.
measurementThe ethanol extract of Vernonia amygdalina contains 99 mg/g of tannins, 70 mg/g of flavonoids, 64 mg/g of saponins, 36 mg/g of phenols, and 32 mg/g of alkaloids.
claimThe bitter taste of Vernonia amygdalina is caused by secondary metabolites, including saponins, tannins, alkaloids, and glycosides, which act as anti-dietary components.
claimPhytochemicals found in Vernonia amygdalina—specifically alkaloids, flavonoids, terpenoids, phenolics, and tannins—exhibit biological activities including antimicrobial effects, antioxidant properties, disease prevention and therapy, free radical scavenging, anticancer activity, and antiviral potential.
claimPhytochemical screening of ethanol and aqueous leaf extracts of Vernonia amygdalina revealed the presence of flavonoids, alkaloids, saponins, tannins, triterpenoids, steroids, and cardiac glycosides.
measurementVernonia amygdalina (bitter leaf) contains 139 mg/g of alkaloids, 180 mg/g of flavonoids, 60 mg/g of saponin, 2.3 mg/g of oxalate, and 167 mg/g of phytate.
claimChemical analysis of Vernonia amygdalina reveals the presence of flavonoids, alkaloids, saponins, tannins, triterpenoids, sesquiterpene lactones, steroids, cardiac glycosides, oxalates, phytates, cyanogenic glycosides, and phenols.
claimThe nutritional composition of Vernonia amygdalina is rich in vital nutrients, vitamins, and minerals, while its biological and pharmacological characteristics are determined by phytochemicals including flavonoids, alkaloids, terpenoids, and phenolic compounds.
claimVernonia amygdalina contains numerous phytochemicals including alkaloids, glycosides, sesquiterpene lactones, steroids, flavonoids, proanthocyanidins, tannins, terpenoids, phenylpropanoids, resins, lignans, furocoumarines, naphthodianthrones, proteins, and peptides.
measurementThe aqueous leaf extract of Vernonia amygdalina contains 27 mg/g of saponins, 46 mg/g of alkaloids, 122 mg/g of flavonoids, 17 mg/g of terpenoids, 12 mg/g of tannins, 48 mg/g of steroids, and 36 mg/g of phenols.
Pharmacological Uses of New Bioactive Compounds from Medicinal ... academia.edu International Academic Publishing House 6 facts
claimAlkaloids are significant compounds in nature and for human life, as discussed in an introductory chapter by Kurek, J. in 2019.
claimSecondary metabolites found in medicinal plants, specifically terpenoids, alkaloids, and phenolics, exhibit antimicrobial, anti-inflammatory, and anticancer effects.
referenceSz and Buda (1971) documented the chemical reaction between alkaloids and potassium tetraiodomercurate.
referenceAryal et al. (2022) published a study in Evidence-Based Complementary and Alternative Medicine titled 'Potential Therapeutic Applications of Plant-Derived Alkaloids against Inflammatory and Neurodegenerative Diseases,' which evaluates the therapeutic potential of alkaloids.
claimSecondary metabolites found in medicinal plants, including flavonoids, tannins, phenolic acids, terpenoids, alkaloids, coumarins, essential oils, and polypeptides, possess antibacterial, anti-inflammatory, antioxidant, anti-cancer, neuroprotective, and immunomodulatory properties.
claimRecent research has identified artemisinin derivatives and new alkaloids as bioactive compounds with therapeutic potential in various diseases.
Investigation of nutritional and phytochemical properties of wild ... nature.com Nature Dec 9, 2025 5 facts
claimSecondary phytochemical screening identifies bioactive compounds such as alkaloids, flavonoids, phenols, saponins, and tannins, which are responsible for the therapeutic efficacy of plants.
claimThe medicinal plants studied in the Renukaji Wildlife Sanctuary contain bioactive compounds including saponins, alkaloids, and flavonoids, as well as essential minerals including Na, N, K, P, Zn, Fe, Cu, Mn, Ca, Mg, and S.
claimPlants contain phytochemicals such as alkaloids, flavonoids, phenols, saponins, and tannins, which often exhibit antioxidant, antimicrobial, and anti-inflammatory properties.
referenceUltra Performance Liquid Chromatography–Photodiode Array (UPLC-PDA) is an analytical technique used to identify and quantify phytochemicals in plant materials by detecting bioactive compounds like polyphenols, flavonoids, and alkaloids based on their UV absorbance and retention time.
claimPhytoconstituents are bioactive compounds found in vegetation, such as flavonoids, alkaloids, and saponins, that possess medicinal properties and contribute to therapeutic effects.
Hallucinogenic Plants and Their Use in Traditional Societies culturalsurvival.org Cultural Survival Feb 19, 2010 3 facts
claimOloliuqui contains alkaloids closely related to the synthetic hallucinogen LSD.
measurementPeyote (Lophophora williamsii) contains as many as 30 active constituents, primarily alkaloids.
claimMost hallucinogens are alkaloids, a family of approximately 5,000 complex organic molecules that also account for the biological activity of most toxic and medicinal plants.
Ethnobotanical study of food plants used in traditional medicine in ... link.springer.com Springer Nov 26, 2025 2 facts
referenceFabaceae species are valued in traditional medicine due to their phytochemical richness, specifically the presence of bioactive compounds such as flavonoids, alkaloids, and coumarins, as noted in the source cited as [31].
claimLeaves are rich sources of secondary metabolites, including polyphenols, alkaloids, carotenoids, and vitamins, which provide antimicrobial, antioxidant, and anti-inflammatory properties, as demonstrated by studies [48, 49].
Pharmacological Uses of New Bioactive Compounds from Medicinal ... ouci.dntb.gov.ua Bhanumati Sarkar, Paramita Biswas, Suman Adhikari · International Academic Publishing House (IAPH) 2 facts
referenceKurek (2019) authored an introductory chapter on the importance of alkaloids in nature and human life.
claimProminent bioactive compounds found in medicinal plants include flavonoids, tannins, phenolic acids, terpenoids, alkaloids, coumarins, essential oils, and polypeptides.
Phytochemical and Pharmacological Studies of Traditionally Used ... heraldopenaccess.us Journal of Food Science & Nutrition 2 facts
claimHerbal plant infusions available as ready-to-serve drinks, instant tea, or squashes possess antidiabetic properties due to the presence of functional ingredients including phenols, flavonoids, tannins, alkaloids, and essential oils, which increase sugar metabolism by stimulating insulin secretion and maximizing sugar excretion through renal diuresis.
claimPreliminary phytochemical analysis indicates that Ocimum basilicum Linn. contains terpenoids, alkaloids, phenolics, flavonoids, tannins, saponin, reducing sugars, cardiac glycosides, steroids, and glycosides.
“Plants of the Gods” and their hallucinogenic powers in ... surgicalneurologyint.com Miguel Faria · Surgical Neurology International Jul 19, 2021 1 fact
claimAlkaloids found in fresh plants and their dried roots cause toxic effects, including nausea, vomiting, tachycardia, and paralysis, as well as psychoactive effects, including hallucinations, delusions, psychosis, and seizures.
Active Plant Principles and Applications in Plant Medicine irispublishers.com Daniela Rebeca Ardelean, Ramona Stef, Monica Butnariu · Iris Publishers May 2, 2024 1 fact
claimThe most important groups of active principles in medicinal and aromatic plants include glucides, pectins, mucilages and gums, fatty oils, volatile oils, resins, organic acids, glycosides, saponins, astringents, bitter principles, vitamins, alkaloids, vegetable dyes, antibiotics, phytoncides, and mineral substances.
A Comprehensive Review on the Therapeutic Properties of ... traditionalmedicine.actabotanica.org Acta Botanica 1 fact
claimMedicinal plants contain various chemical compounds, including alkaloids, flavonoids, terpenoids, and phenolic compounds, which contribute to their medicinal properties.
A critical review of industrial fiber hemp anatomy, agronomic ... bioresources.cnr.ncsu.edu BioResources 1 fact
claimHemp packaging products exhibit antimicrobial activity because hemp contains biologically active compounds such as alkaloids, saponins, and flavones that inhibit bacterial growth.
Phytobioactive compounds as therapeutic agents for human ... onlinelibrary.wiley.com Wiley Apr 17, 2023 1 fact
claimPolyphenols, alkaloids, terpenes, and polysaccharides isolated from medicinal plants exhibit antioxidant, anticancer, cytotoxic, and anti-inflammatory biological activities.
Psychoactive plants in Ancient World: notes from an Ethnobotanist academia.edu Academia.edu 1 fact
referenceNaranjo, C. wrote 'Psychotropic Properties of the Harmala Alkaloids' (1967), which examines the pharmacological effects of alkaloids found in Peganum harmala.
Medicinal Plant - an overview | ScienceDirect Topics sciencedirect.com ScienceDirect 1 fact
claimPlant extracts containing flavonoids, alkaloids, and sterols function as anti-oxidants and anti-inflammatory agents by reducing free radicals.
Medicinal plants meet modern biodiversity science - OUCI ouci.dntb.gov.ua Charles C. Davis, Patrick Choisy · Elsevier BV 1 fact
claimPhytochemical analysis of Dichrostachys cinerea confirms the presence of biologically active compounds including flavonoids, polyphenols, alkaloids, saponins, terpenoids, and tannins.
Wild edible plants for food security, dietary diversity, and nutraceuticals frontiersin.org Frontiers Nov 27, 2025 1 fact
claimEthnomedical products derived from wild edible plants may contain harmful compounds, including alkaloids, monoterpenes, heavy metals, or pesticides.