IL-18 is classified as a pro-inflammatory cytokine, is produced by macrophages, dendritic cells, and epithelial cells, binds to the CD218a (IL-18Ra) receptor, targets monocytes and T cells, and functions in recruiting monocytes and T lymphocytes, synergizing with IL-12 to induce IFN-gamma production, and inhibiting angiogenesis.

Authors

• Person: Not available Organization: Thermo Fisher Scientific
  Pro-Inflammatory Cytokines Overview | Thermo Fisher Scientific - US

Sources

• Pro-Inflammatory Cytokines Overview | Thermo Fisher Scientific - US www.thermofisher.com Thermo Fisher Scientific via serper

Referenced by nodes (7)

• macrophages concept
• dendritic cells concept
• T cells concept
• monocyte concept
• pro-inflammatory cytokine concept
• epithelial cells concept
• IFN-gamma concept