Water supports the evolution of aerobic aquatic life because it allows for high solubility of oxygen and carbon dioxide at room temperature.
Water is a combustion product of hydrogen and oxygen, meaning it does not combust in oxygen, unlike many alternative solvents which are unstable in oxygen-rich atmospheres.
Ammonia is a potential alternative solvent to water for life because it is a polar molecule and is cosmically abundant.
Ammonia is a stronger nucleophile than water, being more inclined to accept an H+ ion and less inclined to donate one.
As of 2026, all known Earth-based life forms utilize carbon compounds for structural and metabolic functions, water as a solvent, and DNA or RNA to control their form.
Silanes, which are silicon analogues to alkanes, react rapidly with water, and long-chain silanes spontaneously decompose.
Water is the combustion product of hydrogen and oxygen, rendering it non-combustible in oxygen-rich environments, whereas many alternative solvents are unstable in such conditions.
Water is spectroscopically transparent, allowing solar radiation to penetrate several meters into the liquid or solid, which aids the evolution of aquatic life.
Water acts as a stronger solvent than hydrocarbons, which facilitates the transport of substances within a cell.
Water functions as an acid when added to liquid ammonia, increasing the concentration of the ammonium cation.
Non-polar hydrocarbon solvents, such as methane and ethane, are potential alternatives to water for life and are known to exist in liquid form on the surface of Titan.
Ammonia and ammoniaβwater mixtures remain liquid at temperatures far below the freezing point of pure water, making them potentially suitable for life on planets and moons outside the water-based habitability zone, such as under the surface of Saturn's moon Titan.
Water is a room-temperature liquid that supports a large population of quantum transition states, whereas cryogenic liquids like methane have lower transition state populations, potentially leading to reaction rates too slow to support life.
Liquid ammonia is a potential alternative solvent for life because it is relatively abundant in the universe and shares chemical similarities with water.
Joop M. Houtkooper and Dirk Schulze-Makuch proposed a hypothesis in 2007 regarding the potential for hydrogen peroxide (H2O2) and water (H2O) mixtures to support extremophiles on Mars.
Ammonia has weaker hydrogen bonds than water, resulting in a heat of vaporization half that of water and a surface tension one-third that of water, which reduces its ability to concentrate non-polar molecules through a hydrophobic effect.
Ammonia functions as an Arrhenius base when added to water, increasing the concentration of the hydroxide anion.
Water supports the evolution of aerobic aquatic life due to its high solubility of oxygen and carbon dioxide at room temperature.
Water functions as an acid when added to liquid ammonia, increasing the concentration of the ammonium cation.
Hydrogen fluoride forms hydrogen bonds with neighboring molecules, similar to water and ammonia.
Water's high heat capacity contributes to environmental temperature stability.
Ammonia is a stronger nucleophile than water, as it is more inclined to accept an H+ ion and less inclined to donate one.
The free energy of formation of liquid water is -237.24 kJ/mol, which contributes to its thermodynamic stability.
It has been proposed that life on Mars may exist using a mixture of water and hydrogen peroxide as a solvent.
Steven Benner's polyelectrolyte theory of the gene asserts that for a genetic biopolymer such as DNA to function in water, it requires repeated ionic charges.
Hydrogen fluoride is cosmically rare compared to water, ammonia, and methane.
Water is chemically reactive and can break down large organic molecules through the process of hydrolysis.
Liquid ammonia is chemically similar to water, can dissolve most organic molecules and many elemental metals, and contains chemical analogues to water-related compounds, such as the amine group (βNH2) being analogous to the hydroxyl group (βOH).
Silanes, which are silicon analogues to alkanes, react rapidly with water, and long-chain silanes spontaneously decompose.
Ammonia functions as an Arrhenius base when added to water, increasing the concentration of the hydroxide anion.
Water's status as a room-temperature liquid allows for a large population of quantum transition states, whereas cryogenic liquids like methane have lower transition state populations that may result in reaction rates too slow to support life.
Water's spectroscopic transparency allows solar radiation to penetrate several meters into the liquid, which aids the evolution of aquatic life.
Water's chemical complexity, including acidβbase chemistry, hydrogen bonding, and van der Waals bonding, provides numerous pathways for evolution, whereas many other solvents have fewer possible reactions.
Ammonia (NH3) forms the amide anion (NH2β) when it donates an H+ ion, which is analogous to the hydroxide anion (OHβ) formed by water.
Water has a high heat capacity, which leads to higher environmental temperature stability.
Scientists debate the effectiveness of methane and other hydrocarbons as a solvent for life compared to water or ammonia.
Ammonia can accept or donate an H+ ion, and when it accepts an H+, it forms the ammonium cation (NH4+), which is analogous to the hydronium ion (H3O+) formed by water.
Acrylonitrile is predicted to have stability and flexibility in liquid methane comparable to that of a phospholipid bilayer in liquid water, potentially allowing it to form cell membranes known as azotosomes.
The tendency of water molecules to form strong hydrogen bonds can interfere with the internal hydrogen bonding required by complex organic molecules.
Hydrogen sulfide is the closest chemical analog to water, though it is less polar and a weaker inorganic solvent.
Ammonia is a hypothetical alternative to water as a biological solvent because it is a polar molecule and is cosmically abundant.
Water ice has a lower density than liquid water, which causes ice to float and prevents bodies of water from freezing solid from the bottom up.
Water possesses a high heat of vaporization, which contributes to the existence of stable lakes and oceans.
Water maintains a liquid state over a large temperature range, which is a property important for life processes.
Water's chemical complexity facilitates numerous reaction pathways, including acidβbase chemistry, H+ cations, OHβ anions, hydrogen bonding, van der Waals bonding, dipoleβdipole interactions, aqueous solvent cages, and hydrolysis.
Water has a high heat of vaporization, which allows for the existence of stable lakes and oceans.
Hydrogen sulfide is a chemical analog of water, though it is less polar and a weaker inorganic solvent, making it a candidate for alternative biochemistry.
Ammonia has weaker hydrogen bonds than water, resulting in a heat of vaporization half that of water and a surface tension one-third that of water, which reduces its ability to concentrate non-polar molecules through a hydrophobic effect.
A 61.2% (by mass) mixture of water and hydrogen peroxide has a freezing point of β56.5 Β°C, tends to super-cool rather than crystallize, and is hygroscopic.