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neurodegenerative diseases
Also known as: neurodegenerative disorders, neurodegenerative disease, neurodegenerative conditions
Facts (27)
Sources
Medicinal plants and human health: a comprehensive review of ... link.springer.com Nov 5, 2025 3 facts
referenceBaicalin and baicalein provide protective effects against neurodegenerative diseases by regulating neuroinflammation, according to research by Yang et al. in 2024.
referenceShoaib et al. (2023) reviewed the use of plant-derived bioactive compounds in managing neurodegenerative disorders, including the molecular mechanisms involved in neuroprotection.
referenceCurcumin is associated with aging and age-related neurodegenerative diseases, specifically Alzheimer's and Parkinson's disease, as reviewed by Turer and Sanlier in their 2025 narrative review.
A Consensus Proposal for Nutritional Indicators to Assess ... - Frontiers frontiersin.org 2 facts
procedureThe 'Diet-Related Morbidity/Mortality Statistics' indicator uses two primary parameters: (1) the prevalence of individuals with physician-diagnosed obesity, cardiovascular diseases (CHD, stroke, hypertension), type II diabetes, osteoporosis, neurodegenerative diseases, and obesity-related cancers; and (2) disability-adjusted life years (DALYs) as a measure of disease burden associated with nutrition-related factors like high blood pressure, high cholesterol (total and LDL), and high blood sugar (insulin resistance/diabetes).
procedureThe 'Diet-Related Morbidity/Mortality Statistics' indicator monitors the occurrence of cardiovascular events, type II diabetes, dyslipidemia, hypertension, osteoporosis, neurodegenerative diseases, and certain cancers as a proxy for the consumption of healthy diets.
Pharmacological Uses of New Bioactive Compounds from Medicinal ... ouci.dntb.gov.ua 2 facts
referenceB. Aryal et al. (2022) investigate the potential therapeutic applications of plant-derived alkaloids against inflammatory and neurodegenerative diseases.
claimDas, S.K., Sen, K., Sanyal, T., Saha, A., & Madhu, N.R. (2024) assert that flavonoids act as neuroprotectants and have salutary effects on age-related neurodegenerative disorders.
Extent and Health Consequences of Chronic Sleep Loss and ... - NCBI ncbi.nlm.nih.gov 2 facts
claimSecondary cases of narcolepsy or hypersomnia can occur in the context of psychiatric disorders (e.g., depression), central nervous system tumors (notably in the hypothalamus), neurodegenerative disorders (e.g., Parkinson’s disease), inflammatory disorders (e.g., multiple sclerosis or paraneoplastic syndromes), traumatic disorders (e.g., head trauma), vascular disorders (e.g., median thalamic stroke), and genetic disorders (e.g., myotonic dystrophy or Prader-Willi syndrome).
measurementIn patients with neurodegenerative conditions, dopaminergic neurons in the substantia nigra and noradrenergic neurons in the locus coeruleus are dramatically reduced in number (Jellinger, 1986).
The New Field of Network Physiology: Building the Human ... frontiersin.org 2 facts
claimNetwork Physiology research investigates the pairwise and network interactions of organ systems and sub-systems, and how these interactions manifest in aging, exercise, sports, and various clinical conditions such as concussion, traumatic brain injury, cardiac arrest, sleep and neurodegenerative disorders, diabetes, obesity, maternal-fetal and neonatal care, sepsis, coma, and multiple organ failure.
claimThe Human Physiolome maps are associated with diseases including neurodegenerative and metabolic disorders, sleep and circadian disorders, cancer, diabetes and obesity, concussion and brain trauma, coma, cardiac arrest, sepsis, and multiple organ failure.
The Profound Interplay Between Sleep and Cognitive Function creyos.com Aug 14, 2025 2 facts
referenceChronically poor sleep is recognized as a risk factor for accelerated cognitive decline and neurodegenerative diseases (Ungvari et al., 2025).
referenceChronic sleep disruption caused by sleep apnea is a serious contributor to cognitive impairment and is recognized as a risk factor for neurodegenerative conditions like Alzheimer's disease (Andrade et al., 2019).
Pharmacological Uses of New Bioactive Compounds from Medicinal ... academia.edu 2 facts
referenceAnthocyanins provide a protective effect against neurodegenerative diseases through the microbial-intestinal-brain axis, as reviewed by Zhong et al. in 2023.
referenceAryal et al. (2022) published a study in Evidence-Based Complementary and Alternative Medicine titled 'Potential Therapeutic Applications of Plant-Derived Alkaloids against Inflammatory and Neurodegenerative Diseases,' which evaluates the therapeutic potential of alkaloids.
Chronic inflammation in the etiology of disease across the life span nature.com Dec 5, 2019 2 facts
claimInnate immune activation is a key factor in neurodegenerative disease, according to Heneka, Kummer, and Latz (2014).
claimSystemic chronic inflammation (SCI) leads to several diseases that represent the leading causes of disability and mortality worldwide, including cardiovascular disease, cancer, diabetes mellitus, chronic kidney disease, non-alcoholic fatty liver disease, and autoimmune and neurodegenerative disorders.
How to reduce inflammation in the body - MD Anderson Cancer Center mdanderson.org Mar 20, 2026 2 facts
What Is Inflammation? Types, Causes & Treatment my.clevelandclinic.org Mar 22, 2024 1 fact
claimChronic inflammation is involved in the disease process of autoimmune diseases (lupus, rheumatoid arthritis, psoriasis, ankylosing spondylitis), cardiovascular diseases (heart disease, high blood pressure), certain cancers, gastrointestinal diseases (Crohn’s disease, inflammatory bowel disease), lung diseases (asthma, chronic obstructive pulmonary disease), mental health conditions (depression, anxiety), metabolic diseases (Type 2 diabetes), and neurodegenerative diseases (Alzheimer’s disease, Parkinson’s disease).
Editorial: Inflammation and chronic disease - Frontiers frontiersin.org Jul 1, 2024 1 fact
claimInflammation is associated with the morbidity and mortality of cardiovascular disease, chronic kidney disease, diabetes mellitus, non-alcoholic fatty liver disease, cancer, autoimmune diseases, neurodegenerative disorders, and behavioral health disorders.
Why At Least 7 Hours of Sleep Is Essential for Brain Health medicine.utah.edu Jun 26, 2023 1 fact
claimSleep deficiency is linked to serious health outcomes, including obesity, hypertension, type 2 diabetes, stroke, and neurodegenerative disorders.
Phytochemical and Pharmacological Studies of Traditionally Used ... heraldopenaccess.us 1 fact
claimMurraya koenigii leaves are investigated for a multi-target approach in treating neurodegenerative diseases, according to a 2022 study by Tan et al.
Why Sleep Is Important for Brain Health - American Brain Foundation americanbrainfoundation.org Mar 16, 2022 1 fact
claimSleep and circadian rhythm dysfunction, such as fragmented sleep or night wakings, may be a risk factor for neurodegenerative disorders like Alzheimer’s and Parkinson’s disease.
Medicinal Plants and Traditional Uses and Modern Applications jneonatalsurg.com Mar 17, 2025 1 fact
referenceDebnath and Mandal (2021) published a comprehensive review titled 'Traditional herbal remedies for treating neurodegenerative diseases: A comprehensive review' in the Journal of Herbal Medicine.
Dietary Guidelines and Quality - Principles of Nutritional Assessment nutritionalassessment.org 1 fact
claimHigher adherence to the DASH diet is linked to lower risks for all-cause mortality, cardiovascular disease incidence or mortality, cancer incidence or mortality, type 2 diabetes, and neurodegenerative disease, according to Morze et al. (2020).
Chronic Inflammation: How to Test For it and Prevent it medichecks.com Jan 31, 2024 1 fact
claimChronic inflammation is associated with various conditions, including autoimmune diseases (thyroid conditions, rheumatoid arthritis), cardiovascular diseases (high blood pressure, heart disease), gastrointestinal disorders (inflammatory bowel disease, Crohn's disease, ulcerative colitis), lung diseases (COPD, asthma), mood conditions (depression), metabolic diseases (type 2 diabetes), neurodegenerative diseases (Parkinson’s disease), and some cancers.