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hypothalamic-pituitary-adrenal axis
Also known as: HPA axis
Facts (24)
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Extent and Health Consequences of Chronic Sleep Loss and ... - NCBI ncbi.nlm.nih.gov 7 facts
claimThe activation of the sympathetic nervous system, hypothalamic-pituitary-adrenal axis, and adipocytes due to Obstructive Sleep Apnea (OSA) leads to the release of catecholamines, cortisol, and inflammatory cytokines, which may mediate the development of glucose intolerance, insulin resistance, and type 2 diabetes.
claimPerlis et al. (2005) hypothesize that chronic insomnia increases activity of the hypothalamic-pituitary-adrenal axis, which contributes to the development of depression.
claimThe biochemical cascade by which Obstructive Sleep Apnea (OSA) disrupts glucose metabolism begins with intermittent hypoxia and recurrent sleep arousals (sleep fragmentation), which stimulate the sympathetic nervous system, the hypothalamic-pituitary-adrenal axis, and adipocytes.
claimOne hypothesis for the link between insomnia and depression is that chronic insomnia increases activity of the hypothalamic-pituitary-adrenal axis, which contributes to depression (Perlis et al., 2005).
measurementAdults with insomnia have higher levels of cortisol and adrenocorticotropic hormone (ACTH) over a 24-hour period compared to normal sleepers, indicating activation of the hypothalamic-pituitary-adrenal axis.
claimVgontzas A.N., Bixler E.O., Lin H.M., Prolo P., Mastorakos G., Vela-Bueno A., Kales A., and Chrousos G.P. found that chronic insomnia is associated with nyctohemeral activation of the hypothalamic-pituitary-adrenal axis, as published in the Journal of Clinical Endocrinology and Metabolism in 2001.
claimPunjabi and Beamer (2005) describe the biochemical cascade of obstructive sleep apnea (OSA) as beginning with intermittent hypoxia and recurrent sleep fragmentation, which stimulates the sympathetic nervous system, the hypothalamic-pituitary-adrenal axis, and adipocytes.
Stress, Lifestyle, and Health – Introduction to Psychology open.maricopa.edu 4 facts
claimThe physiological mechanisms of stress involve the sympathetic nervous system and the hypothalamic-pituitary-adrenal (HPA) axis.
claimRats that exercised for six weeks showed a decrease in hypothalamic-pituitary-adrenal responsiveness to mild stressors in a study by Campeau et al. (2010).
claimThe hypothalamic-pituitary-adrenal (HPA) axis is an endocrine system that activates in response to stress, though it operates more slowly than the sympathetic nervous system.
claimStress hormones released during hypothalamic-pituitary-adrenal (HPA) axis activation inhibit the production of lymphocytes, which are white blood cells essential for the immune response, as noted by Everly and Lating (2002).
Stress, Lifestyle, and Health – Psychology 2e OpenStax pressbooks.cuny.edu 4 facts
claimThe physiological mechanisms of stress involve the sympathetic nervous system and the hypothalamic-pituitary-adrenal (HPA) axis.
claimStress hormones released during hypothalamic-pituitary-adrenal (HPA) axis activation can adversely impact immune function by inhibiting the production of lymphocytes, which are white blood cells essential to the immune response.
claimThe hypothalamic-pituitary-adrenal (HPA) axis is an endocrine system that responds to stress more slowly than the sympathetic nervous system.
claimThe fight-or-flight response involves the coordinated activity of both the sympathetic nervous system and the hypothalamic-pituitary-adrenal (HPA) axis.
Short- and long-term health consequences of sleep disruption dovepress.com May 19, 2017 3 facts
referenceVgontzas et al. (2001) found that chronic insomnia is associated with nyctohemeral activation of the hypothalamic-pituitary-adrenal axis.
claimThe health consequences of sleep disruption involve the activation of the sympathetic nervous system, the sympathoadrenal system, and the hypothalamic–pituitary–adrenal axis.
claimSleep disruption is associated with increased activity of the sympathetic nervous system and the hypothalamic–pituitary–adrenal axis, as well as metabolic effects, changes in circadian rhythms, and proinflammatory responses.
Stress: Its Negative Impact on Your Mental & Physical Health cwcare.net Jun 7, 2023 2 facts
claimThe activation of the hypothalamic-pituitary-adrenal (HPA) axis results in increased production of steroid hormones known as glucocorticoids, which include cortisol, commonly referred to as the “stress hormone.”
claimWhen an individual perceives a situation as challenging, threatening, or uncontrollable, the brain initiates a cascade of events involving the hypothalamic-pituitary-adrenal (HPA) axis, which is the primary driver of the endocrine stress response.
Self-awareness, self-regulation, and self-transcendence (S-ART) frontiersin.org 1 fact
claimThe psychological processes of decentering and non-attachment reduce sympathetic tone and suppress hypothalamic-pituitary-adrenal (HPA) axis-mediated mobilization.
Physiology, Male Reproductive System - StatPearls - NCBI Bookshelf ncbi.nlm.nih.gov 1 fact
claimThe hypothalamic-pituitary-adrenal axis is controlled by the hypothalamus and anterior pituitary, functioning similarly to the hypothalamic-pituitary-gonadal axis.
Implications for Mental Health and Coping Strategies | OxJournal oxjournal.org Aug 12, 2024 1 fact
claimChronic stress causes continuous activation of the hypothalamic-pituitary-adrenal (HPA) axis, resulting in elevated, persistent levels of cortisol.
Evolutionary psychology - Wikipedia en.wikipedia.org 1 fact
claimMammals experience separation anxiety from guardians, which triggers distress, signals the hypothalamic-pituitary-adrenal axis, and induces emotional and behavioral changes that help the mammal cope with separation.