The biochemical cascade by which Obstructive Sleep Apnea (OSA) disrupts glucose metabolism begins with intermittent hypoxia and recurrent sleep arousals (sleep fragmentation), which stimulate the sympathetic nervous system, the hypothalamic-pituitary-adrenal axis, and adipocytes.

Authors

• Person: Colten HR, Altevogt BM Organization: National Academies Press
  Extent and Health Consequences of Chronic Sleep Loss and ... - NCBI

Sources

• Extent and Health Consequences of Chronic Sleep Loss and ... - NCBI www.ncbi.nlm.nih.gov Colten HR, Altevogt BM · National Academies Press via serper

Referenced by nodes (5)

• obstructive sleep apnea concept
• sleep fragmentation concept
• sympathetic nervous system concept
• hypothalamic-pituitary-adrenal axis concept
• glucose metabolism concept