concept

global cognition

Also known as: global cognition scores, global cognition score

Facts (33)

Sources

Improvement in sleep duration was associated with higher cognitive ... aging-us.com Aging Oct 20, 2020 33 facts

claimA transition from short sleep duration (SSD) to long sleep duration (LSD) was associated with lower global cognition scores, including on episodic memory, figure drawing, and TICS tests.

claimThe association between changes in sleep duration (≥ 2 hours) and lower global cognition scores was consistent across all three cognition tests used in the study models.

referenceThe study used generalized estimating equations (GEE) to analyze the associations between baseline sleep duration and longitudinal global cognition.

claimAmong participants who were moderate sleepers (6-8 hours) at baseline (Wave 1), increasing or decreasing sleep duration by 2 or more hours by Wave 2 was associated with lower global cognition scores compared to participants who did not change their sleep duration.

measurementThe global cognition score in the CHARLS study is the sum of the episodic memory, figure drawing, and TICS test scores, ranging from 0 to 21.

measurementIn a study of participants who slept 7 hours or more in Wave 1, higher sleep duration was associated with lower scores in global cognition (β=-0.47, P<0.001 for model 1; β=-0.28, P<0.001 for model 2) and on all three cognitive tests.

procedureThe study utilized three statistical models to analyze data: Model 1 adjusted for age and sex; Model 2 adjusted for Model 1 variables plus education, marital status, residential area, depression, IADLs, use of tranquilizers, smoking, alcohol consumption, hypertension, dyslipidaemia, heart disease, and stroke; and Model 3 adjusted for Model 2 variables plus baseline global cognition score.

measurementA change from short sleep duration to long sleep duration is associated with lower global cognition scores (β=-0.94, P <0.001) in individuals aged 45 and older.

claimThe study identified an inverted-U-shaped association between baseline sleep duration and global cognition over 4 years among Chinese participants, affecting domains including episodic memory, figure drawing, and TICS, though baseline sleep duration did not increase rates of cognitive decline.

claimFor short sleepers, a consistent change to moderate sleep duration (MSD) was associated with high global cognition scores, equivalent to 4-10 years of cognitive ageing, with improvements in figure drawing and TICS domains.

claimFor participants identified as short sleepers (sleeping <6 hours) in Wave 1, a change in sleep duration of 2 or more hours in Wave 2 or Wave 3 was associated with lower global cognition scores.

measurementA change in sleep duration of 2 or more hours between Wave 1 and Wave 2 is associated with a decline in global cognition scores equivalent to approximately 9 years of cognitive aging.

measurementA change from short sleep duration to moderate sleep duration is associated with better global cognition scores (β=0.54, P <0.01) in individuals aged 45 and older.

measurementLong sleepers, defined as those sleeping more than 8 hours per night in Wave 1, had lower global cognition scores compared to moderate sleepers (6-8 hours) in the study.

measurementThe effect of short sleep duration on global cognition scores was equivalent to being 5 to 9 years older compared to the moderate sleep-duration group.

measurementParticipants who slept 6-8 hours per night in Wave 1 exhibited the highest global cognition scores in the study.

referenceThe global cognition score used in the China Health and Retirement Longitudinal Study (CHARLS) assessed episodic memory, visuospatial abilities, calculation, orientation, and attention.

measurementAmong participants who slept less than 6 hours at baseline, those in the 'Benefit 2' group had higher global cognition scores in Wave 3 compared to the 'No-change' group (β=0.55, P<0.01 for model 1; β=0.54, P<0.01 for model 2; β=0.38, P<0.05 for model 3).

measurementThe effect of long sleep duration on global cognition scores was equivalent to being 6 to 11 years older compared to the moderate sleep-duration group.

measurementA change from long sleep duration to short sleep duration is associated with lower global cognition scores (β=-1.38, P <0.01) in individuals aged 45 and older.

measurementAmong participants who slept more than 8 hours in Wave 1, the 'Excessive' sleep group showed lower global cognition in Wave 3 compared to the 'No-change' group (β=-1.38, P<0.01 for model 2; β=-1.17, P<0.01 for model 3), specifically regarding episodic memory.

measurementFor individuals with moderate sleep duration, a 2-hour or greater increase in sleep duration is associated with lower global cognition scores (β=-0.89, P <0.001).

measurementShort sleepers, defined as those sleeping less than 6 hours per night in Wave 1, had lower global cognition scores compared to moderate sleepers (6-8 hours) in the study.

claimThe study titled 'Improvement in sleep duration was associated with higher cognitive...' identified an inverted-U shaped association between sleep duration and global cognition scores in Wave 1, as visualized by generalized additive models.

measurementThe sleep-duration-by-time interaction was not statistically significant (P > 0.10), indicating no significant association between sleep duration at Wave 1 and the rate of reduction in global cognition scores over a 4-year period.

claimThe researchers used the global cognition score as the primary outcome measure in their study on sleep duration and cognitive function.

referenceThe study used generalized additive models (GAM) to analyze the association between sleep duration and global cognition, which indicated a non-linear fit.

claimIn the study analysis of changes from Wave 1 to Wave 3, changes in sleep duration were associated with global cognition scores, with the association remaining significant for episodic memory and TICS tests in models 2 and 3, but not for the figure-drawing test.

measurementIn a study of participants who slept 7 hours or less in Wave 1, shorter sleep duration was associated with lower scores in global cognition (β=0.48, P<0.001 for model 1; β=0.28, P<0.001 for model 2) and on all three cognitive tests.

claimFor participants identified as long sleepers in Wave 1, changes in sleep duration had no significant effect on global cognition scores.

claimFor moderate sleepers, a change in sleep duration of 2 hours or more was significantly associated with lower global cognition and lower scores on episodic memory, figure drawing, and TICS tests.

measurementAmong participants who slept less than 6 hours at baseline, those in the 'Excessive' change group had lower global cognition scores in Wave 3 compared to the 'No-change' group (β=-1.91, P<0.001 for model 1; β=-0.94, P<0.001 for model 2; β=-0.53, P<0.05 for model 3).

measurementFor individuals with moderate sleep duration, a 2-hour or greater decrease in sleep duration is associated with lower global cognition scores (β=-0.70, P <0.001).