concept

CRP

Also known as: C-reactive protein

Facts (16)

Sources

Integrating allostasis and emerging technologies to study complex ... nature.com Nature Nov 5, 2025 8 facts

claimThe allostatic load index, calculated by summing high-risk physiological biomarkers including systolic and diastolic blood pressure, BMI, fasting glucose, total cholesterol, HDL cholesterol, and CRP, was found to be elevated in black breast cancer survivors compared to black women without a cancer history.

claimThe current immune allostatic load index is limited to a specific set of immune biomarkers, including CRP, IL-6, and TNF-α.

claimAcute phase HIV infection triggers immune activation, evidenced by the proliferation of CD4+ T-cells and elevated levels of inflammatory biomarkers such as IL-6, D-dimer, and CRP.

claimCurrent allostatic load indices fail to fully capture the complexity of immune allostasis in chronic conditions like Long COVID, HIV, or cancer because they rely on a narrow subset of immune biomarkers such as CRP, IL-6, and TNF-α.

claimLong COVID exhibits widespread dysregulation of the immune system, demonstrated by prolonged immune cell activation and increased levels of immune-related factors such as IL-4, interferons (IFNs), and CRP.

claimAllostatic load, characterized by metabolic and inflammatory dysregulation such as elevated blood glucose, CRP, or altered lipid levels, promotes a tumor-permissive environment.

perspectiveCurrent indices of immune allostasis, which rely on a narrow subset of biomarkers such as CRP, IL-6, and TNF-α, fail to fully capture the complexity of immune allostasis in chronic conditions like Long COVID, HIV, or cancer.

claimThe current allostatic load index is limited to biomarkers such as CRP, IL-6, and TNF-α, creating a need to incorporate additional biomarkers like activated T-cell subset frequencies and a broader range of cytokines to accurately capture immune allostatic load.

Chronic Inflammation - StatPearls - NCBI Bookshelf ncbi.nlm.nih.gov National Library of Medicine 3 facts

claimHigher intake of omega-3 fatty acids, found in fish oil, is associated with lowering levels of TNF-alpha, C-reactive protein (CRP), and IL-6.

claimGreen and black tea polyphenols are associated with a reduction in C-reactive protein (CRP) levels in human clinical studies.

claimMetformin is used to treat type II diabetic patients with dyslipidemia and low-grade inflammation, and it reduces circulating TNF-alpha, IL-1beta, CRP, and fibrinogen.

Inflammatory Markers | Choose the Right Test arupconsult.com ARUP Consult Jun 16, 2025 2 facts

claimMarkers of inflammation beyond CRP, ESR, and PCT include serum amyloid A, cytokines, alpha-1-acid glycoprotein, plasma viscosity, ceruloplasmin, hepcidin, and haptoglobin.

claimHigh costs, limited availability, and lack of standardization limit the practical clinical use of inflammatory markers other than CRP, ESR, and PCT.

Should you be tested for inflammation? health.harvard.edu Harvard Health Publishing Mar 29, 2022 1 fact

claimInflammation tests, such as ESR and CRP, can produce false negative results when inflammation is present and false positive results when inflammation is absent.

What causes chronic inflammation, and why it matters health.osu.edu The Ohio State University Wexner Medical Center Jan 13, 2025 1 fact

claimBlood tests for inflammation, such as ESR and CRP, cannot identify the specific cause of inflammation and elevated markers do not always indicate the presence of a disease.

Inflammation: Types, symptoms, causes, and treatment medicalnewstoday.com Medical News Today 1 fact

claimDoctors may assess inflammation levels by measuring biomarkers, such as C-reactive protein (CRP).