Interleukin-37 (IL-37/IL-1F7) is an anti-inflammatory cytokine produced by B-cells, NK cells, and monocytes that binds to CD218a (IL-18Ra) and potentially SIGGR, and is believed to act as a negative regulator inside the cell by interacting with SMAD3 activated downstream of TGFβ activity.

Authors

• Person: Not available Organization: Thermo Fisher Scientific
  Pro-Inflammatory Cytokines Overview | Thermo Fisher Scientific - US

Sources

• Pro-Inflammatory Cytokines Overview | Thermo Fisher Scientific - US www.thermofisher.com Thermo Fisher Scientific via serper

Referenced by nodes (6)

• monocyte concept
• B cells concept
• anti-inflammatory cytokines concept
• interleukin-1β concept
• NK cells concept
• TGF-β concept