Pluripotent stem cells (PSCs) and cancer cells may maintain low levels of mitochondrial DNA (mtDNA) replication by reducing the activity of the nuclear-encoded mitochondrial polymerase gamma A (POLGA) through hypermethylation at its exon 2.

Authors

• Person: Not available Organization: Springer
  Mitochondria and the dynamic control of stem cell homeostasis

Sources

• Mitochondria and the dynamic control of stem cell homeostasis link.springer.com Springer via serper

Referenced by nodes (3)

• pluripotent stem cells concept
• cancer cells concept
• mitochondrial DNA concept