Silybin induces autophagy in breast cancer via ROS-dependent mitochondrial dysfunction and loss of ATP involving BNIP3; it also prevents TPA and PMA induced MMP-9 expression and VEGF secretion via inactivation of the Raf/MEK/ERK pathway and blockade of AP-1 activation via MAPK signaling pathways, according to Wang et al. [101].

Authors

• Person: Not available Organization: Journal of Food Science & Nutrition
  Phytochemical and Pharmacological Studies of Traditionally Used ...

Sources

• Phytochemical and Pharmacological Studies of Traditionally Used ... www.heraldopenaccess.us Journal of Food Science & Nutrition via serper

Referenced by nodes (6)

• breast cancer concept
• Silibinin concept
• mitogen-activated protein kinase (MAPK) signaling pathway concept
• autophagy concept
• ATP concept
• mitochondrial dysfunction concept