Endothelial dysfunction contributes to heart failure development by disrupting endothelial nitric oxide synthase (eNOS) activity, which reduces nitric oxide availability, increases reactive oxygen species production, and activates inflammatory cascades involving NF-κb signaling and the expression of adhesion molecules ICAM1 and VCAM1.

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• Person: Not available Organization: Springer
  Medicinal plants and human health: a comprehensive review of ...

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• Medicinal plants and human health: a comprehensive review of ... link.springer.com Springer via serper

Referenced by nodes (4)

• reactive oxygen species concept
• heart failure concept
• nitric oxide concept
• NF-κB signaling pathway concept