Knowledge Tree
nitric oxide
Facts (12)
Sources
Vernonia amygdalina: a comprehensive review of the ... frontiersin.org 5 facts
measurementVernoamyoside D inhibits nitric oxide production by 37.6% in LPS-induced RAW264.7 macrophages at 50 µM, while the positive control N-monomethylL-arginine exhibits 57.34% inhibition.
measurementVernoamyoside C inhibits nitric oxide production by 50.0% in LPS-induced RAW264.7 macrophages at 50 µM, while the positive control N-monomethylL-arginine exhibits 57.34% inhibition.
measurementVernoamyoside B inhibits nitric oxide production by 24.5% in LPS-induced RAW264.7 macrophages at 50 µM, while the positive control N-monomethylL-arginine exhibits 57.34% inhibition.
measurementVernoamyoside A inhibits nitric oxide production by 20.5% in LPS-induced RAW264.7 macrophages at 50 µM, while the positive control N-monomethylL-arginine exhibits 57.34% inhibition.
claimVernoamyoside A, B, C, and D inhibit the production of nitric oxide in LPS-induced RAW264.7 macrophages, demonstrating an anti-inflammatory effect.
Medicinal plants and human health: a comprehensive review of ... link.springer.com Nov 5, 2025 3 facts
claimEndothelial dysfunction contributes to heart failure development by disrupting endothelial nitric oxide synthase (eNOS) activity, which reduces nitric oxide availability, increases reactive oxygen species production, and activates inflammatory cascades involving NF-κb signaling and the expression of adhesion molecules ICAM1 and VCAM1.
claimFlavonoids improve vascular function and regulate blood pressure by augmenting endothelial nitric oxide synthase (eNOS) activity, diminishing nitric oxide breakdown, increasing eNOS expression, improving enzyme coupling, and supplying cofactors for nitric oxide synthesis.
claimCertain phytochemicals stimulate endothelium-derived hyperpolarizing factor (EDHF) pathways by activating calcium-activated potassium channels, which causes smooth muscle hyperpolarization and vasodilation independently of nitric oxide and prostacyclin pathways.
Phytochemical and Pharmacological Studies of Traditionally Used ... heraldopenaccess.us 2 facts
claimVitexnegheteroin E exhibits antioxidant activity and inhibitory activities on lipopolysaccharide-induced nitric oxide production.
claimEstragole, methyl cinnamate, methyl eugenol, α-bergamotene, α-cadlnol, linalool, eugenol, and linoleic acid in Ocimum basilicum Linn. exhibit anti-inflammatory activity by inhibiting pro-inflammatory mediators, stimulating anti-inflammatory cytokines, decreasing nitric oxide production, and inhibiting lipoxygenase and cyclooxygenase enzymes, according to Mueller et al., Umamageswari et al., and Eftekhar et al.
Ethnobotanical and Food Composition Monographs of Selected ... ouci.dntb.gov.ua 1 fact
referenceF. Conforti et al. published a study in 2011 in Food Chemistry on the bioactive phytonutrients (omega fatty acids, tocopherols, polyphenols) of non-cultivated Mediterranean vegetables, including their in vitro inhibition of nitric oxide production and free radical scavenging activity.
A Comprehensive Review on the Therapeutic Properties of ... traditionalmedicine.actabotanica.org 1 fact
referenceSreejayan and M. N. Rao published a study on nitric oxide scavenging by curcuminoids in the Journal of Medicinal Chemistry in 1994.