concept

vitamin B12

Also known as: vitamin B-12

Facts (12)

Sources
How do the indices based on the EAT-Lancet recommendations ... medrxiv.org medRxiv May 14, 2024 5 facts
claimEAT-Lancet indices demonstrate an inverse relationship with the nutritional adequacy of zinc and vitamin B-12, regardless of the scoring system used.
measurementThe HSDI and ELDS indices, which are based on binary scoring, correlated inversely with several nutrients including protein, DHA, EPA+DHA, riboflavin, niacin, pantothenic acid, vitamin B-6, vitamin B-12, vitamin D, iodine, phosphorus, zinc, calcium, and iron.
measurementHigher scores on dietary indices were associated with higher nutritional quality and lower environmental impact, but were associated with unfavourable results for zinc intake, vitamin B12, and water use.
measurementThe ELD-I index correlated inversely with linoleic acid, vitamin B12, phosphorus, carbohydrates, and sodium, while the WISH index correlated inversely with niacin, and the PHDI index correlated inversely with total fat.
claimAcross ELD-I quintiles, protein, LA, vitamin B-12, carbohydrates, and sodium showed negative trends of small magnitude, while zinc showed a negative trend with a moderate effect size; iron and proteins showed no significant trends.
Immunity In Depth | Linus Pauling Institute lpi.oregonstate.edu Linus Pauling Institute 3 facts
claimPatients with diagnosed vitamin B12 deficiency, such as pernicious anemia or megaloblastic anemia, exhibit suppressed natural killer cell activity and decreased numbers of circulating lymphocytes.
claimImmunomodulatory effects caused by vitamin B12 deficiency, such as suppressed natural killer cell activity and decreased lymphocyte counts, are corrected by treating the vitamin deficiency.
claimVitamin B12 functions as a coenzyme for the synthesis of methionine from homocysteine and for the conversion of L-methylmalonyl-CoA to succinyl-CoA.
History of modern nutrition science—implications for current ... bmj.com BMJ Jun 13, 2018 2 facts
claimThe identification of vitamins in animal and human studies established the nutritional basis for deficiency diseases, leading to dietary strategies to address beriberi (vitamin B1), pellagra (vitamin B3), scurvy (vitamin C), pernicious anaemia (vitamin B12), and rickets (vitamin D).
claimIn lower-income countries, vitamin supplementation presents specific risks, including potential harms from high-dose vitamin A, the risk of iron exacerbating infections like malaria, and safety concerns regarding folic acid flour fortification potentially worsening neurological and cognitive deficits in individuals with low vitamin B12 levels.
The Role of Nutrition in Child Development inspirechildren.com Inspire Children Jul 8, 2024 1 fact
claimIron, iodine, and vitamins B6 and B12 are vital for cognitive functions in children, including concentration, memory, and problem-solving.
Dietary diversity insufficiently explains differences in prevalence of ... journals.plos.org PLOS Global Public Health 1 fact
claimAnaemia in pregnancy is linked to poor dietary intake, specifically micronutrient deficiencies including iron, folate, vitamin B12, and zinc.