concept

oxidative stress

Also known as: antioxidative stress

Facts (30)

Sources
Medicinal plants and human health: a comprehensive review of ... link.springer.com Springer Nov 5, 2025 6 facts
referenceGu et al. (2021) conducted a multidimensional analysis of the antioxidative stress mechanisms behind resveratrol, published in the Journal of Food Quality.
claimGinkgolides from Ginkgo biloba and baicalin from Scutellaria baicalensis protect the blood–brain barrier by stabilizing tight junction complexes and decreasing oxidative stress and inflammation.
referenceNuclear factor erythroid 2-related factor 2 (Nrf2) signaling plays a role in heavy metals-induced oxidative stress, according to the 2024 study by Tripathi et al.
claimFlavonoids, including quercetin from onions and apples, rutin from buckwheat, and anthocyanins from blueberries and blackberries, bolster blood–brain barrier integrity by fortifying tight junction proteins and diminishing oxidative stress-induced permeability.
claimOxidative stress and inflammation are interrelated processes that exacerbate each other to create pathological cycles facilitating disease advancement.
perspectivePhytochemical therapies targeting both oxidative stress and inflammation are more effective than single-target strategies.
Phytochemical and Pharmacological Studies of Traditionally Used ... heraldopenaccess.us Journal of Food Science & Nutrition 5 facts
referenceMurraya koenigii (L.) Spreng. contains the active compounds koenimbidine, murrayacine, and murrayazolinine, which exhibit anti-diabetic activity by decreasing oxidative stress through the modulation of paraoxonase I activity, as reported by Patel et al.
claimSilymarin inhibits Mayaro virus (MAYV) replication and attenuates MAYV-induced oxidative stress, according to Camini et al. [96].
claimSilymarin exhibits antiviral activity against the Mayaro virus and provides a protective effect against virus-induced oxidative stress, according to a 2018 study by Camini FC et al.
claimRosmarinic acid, estragole, linalool, eugenol, methyl cinnamate, linoleic acid, α-cadinol, and α-bergamotene exhibit antioxidant activity by scavenging free radicals and protecting against oxidative stress through the increase of antioxidative defense enzymes.
claimSilymarin, silybin, and 2,3-dehydrosilybin reduce immunosuppression and oxidative stress in mouse skin, according to Katiyar et al. [107].
Medicinal plants: bioactive compounds, biological activities ... frontiersin.org Frontiers in Immunology 3 facts
claimThe aqueous extract from cinnamon bark combats diabetes, reduces oxidative stress, and alleviates inflammation.
claimSantra et al. demonstrated that plumbagin, derived from the plant Plumbago zeylanica, produces oxidative stress in Candida albicans, leading to fungal cell death.
claimCinnamon bark water extract is efficacious in managing diabetes, reducing oxidative stress, and mitigating inflammation, while showing efficacy against Staphylococcus aureus and Pseudomonas aeruginosa due to ionic interactions.
What Are The Global Impacts of The Western Diet On Health? rupahealth.com Rupa Health 3 facts
claimCoQ10 is an antioxidant that may support metabolic health and help manage oxidative stress levels.
claimHigh sugar intake may create pro-inflammatory substances that induce oxidative stress, which can lead to health issues such as type 2 diabetes.
claimThe Organic Acids Test (OAT) provides an analysis of metabolic health by analyzing biomarkers associated with vitamins, minerals, and oxidative stress levels to detect metabolic imbalances.
Pharmacological Uses of New Bioactive Compounds from Medicinal ... academia.edu International Academic Publishing House 2 facts
referenceMarkesbery, W. R. (1997) published the study 'Oxidative Stress Hypothesis in Alzheimer's Disease' in Free Radical Biology and Medicine, 23(1), 134.
referenceTeixeira et al. (2019) explore future therapeutic perspectives for Alzheimer's disease by targeting the oxidative stress hypothesis.
A Comprehensive Review on the Therapeutic Properties of ... traditionalmedicine.actabotanica.org Acta Botanica 2 facts
claimGreen tea (Camellia sinensis), Ginkgo (Ginkgo biloba), and Aloe vera are rich in antioxidants, which help neutralize harmful free radicals, reduce oxidative stress, prevent cellular damage, and provide anti-aging effects.
claimCurcumin exhibits antioxidant activity that protects the body against oxidative stress and supports cardiovascular health.
Immunity In Depth | Linus Pauling Institute lpi.oregonstate.edu Linus Pauling Institute 2 facts
claimAltered cytokine production caused by zinc deficiency can contribute to oxidative stress and inflammation.
claimHypertrophied adipose tissue contributes to an inflammatory state through four mechanisms: (1) altered adipokine secretion, specifically increased pro-inflammatory leptin and reduced anti-inflammatory adiponectin; (2) release of free fatty acids that induce systemic inflammation; (3) increased endoplasmic reticulum stress triggered by adipocyte expansion, leading to oxidative stress and inflammation; and (4) increased inflammatory gene expression and immune cell activation in hypoxic regions.
Nutraceutical Compounds of edible wild plants collected in Central ... wildlife-biodiversity.com Journal of Wildlife and Biodiversity Sep 26, 2024 1 fact
referenceIborra, Palacio, and Martínez (2005) studied the link between oxidative stress and autoimmune response in infertile women.
Understanding the Inflammatory and Healing Process - Myo-Fit myofittherapy.com MyoFit Therapy Nov 12, 2024 1 fact
claimChronic inflammation increases the production of free radicals, which causes oxidative stress that damages cells and hinders the healing process.
Bridging the Gap Between LLMs and Evolving Medical Knowledge arxiv.org arXiv Jun 29, 2025 1 fact
claimThe generation of free radicals is related to the cross-linking of DNA due to oxidative damage affecting DNA integrity, and LLM analysis of this relationship received an 8.5/10 relevance rating for its explanation of oxidative stress mechanisms.
Research reveals devastating impact of Western diet on human health news-medical.net News-Medical.net Jun 18, 2023 1 fact
claimThe Western diet is often high in pro-oxidant compounds that increase the production of free radicals, such as reactive oxygen species (ROS) and reactive nitrogen species (RNS), leading to increased oxidative stress throughout the body.
Effects of psychedelics on neurogenesis and broader neuroplasticity link.springer.com Springer Dec 19, 2024 1 fact
claimSchiavone et al. (2020) found that intermittent administration of 30 mg/kg ketamine to neonatal rats (P7, P9, P11) caused a two-fold increase in NOX2 that persisted into adulthood, leading to neurochemical imbalances and oxidative stress.
How do the indices based on the EAT-Lancet recommendations ... medrxiv.org medRxiv May 14, 2024 1 fact
claimA higher Composite Dietary Antioxidant Index (CDAI) score suggests a greater bioavailability of antioxidants in the diet, which implies a potentially higher level of defense against oxidative stress and health protection.
Western diet – Knowledge and References - Taylor & Francis taylorandfrancis.com Melissa G. Hunt, Aaron T. Beck · Taylor & Francis 1 fact
claimLong-term consumption of high-fat and high-carbohydrate foods, characteristic of the Western diet, is associated with obesity, insulin resistance, hypertriglyceridemia, non-alcoholic fatty liver disease (NAFLD), and non-alcoholic steatohepatitis (NASH), as well as inflammatory and oxidative stress conditions.