Knowledge Tree
neuroimaging
Also known as: neuroimaging technology
Facts (21)
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Neuroimaging in psychedelic drug development: past, present, and ... nature.com Sep 27, 2023 10 facts
referenceR.L. Carhart-Harris, S. Muthukumaraswamy, L. Roseman, M. Kaelen, W. Droog, K. Murphy, et al. published 'Neural correlates of the LSD experience revealed by multimodal neuroimaging' in the Proceedings of the National Academy of Sciences in 2016.
claimThe proposed neuroimaging studies of psychedelics are feasible with current methods, such as combined PET/MR imaging systems and PET ligands, though they require significant resources and investment.
claimNeuroimaging studies in psychedelic drug development can be adapted by using different PET ligands specific to the pharmacology of the compounds, utilizing other MRI modalities, or employing particular tasks and stimuli.
perspectiveThe authors of the article 'Neuroimaging in psychedelic drug development: past, present, and ...' state that the history of imaging-based biomarkers in psychiatry is mixed, making the feasibility of using such biomarkers for individual-level assessment uncertain.
claimNeuroimaging technology has played a key role in the modern understanding and development of psychedelic therapies.
procedureIn clinical trials involving psychedelics, neuroimaging scans are typically conducted before and after treatment rather than during acute dosing to serve as an objective index of treatment effects.
claimThe use of neuroimaging in clinical trials provides scientific results, informs theories of psychedelic effects, and produces visually-arresting results that are reproduced in mainstream media.
referenceThe article 'Neuroimaging in psychedelic drug development: past, present, and future' by Wall, M.B., Harding, R., Zafar, R. et al. was published in Molecular Psychiatry, volume 28, pages 3573–3580, in 2023.
claimRecent MRI technical innovations, including accelerated scanning with multiband sequences, increased signal-to-noise with multi-echo sequences, and standardized processing pipelines, provide additional capabilities and rigor for neuroimaging.
claimThe modern development of psychedelic therapy in the early 21st century has occurred concurrently with the use of advanced neuroimaging research methods.
Self-awareness, self-regulation, and self-transcendence (S-ART) frontiersin.org 2 facts
The Mechanisms of Psychedelic Visionary Experiences - Frontiers frontiersin.org Sep 27, 2017 2 facts
referenceA systematic review of human studies by dos Santos et al. (2016) examined the relationship between classical hallucinogens and neuroimaging.
referenceRiba et al. (2004) conducted a functional neuroimaging study using low-resolution electromagnetic tomography to measure the effects of the South American psychoactive beverage ayahuasca on regional brain electrical activity in humans.
The Montreal model: an integrative biomedical-psychedelic ... frontiersin.org 2 facts
claimRecent neuroimaging research indicates that despite pharmacological differences, serotonergic psychedelics and ketamine share neural features, specifically heightened neural signal diversity, reduced within-network connectivity, and enhanced between-network connectivity.
referenceFrancois et al. (2016) conducted a cross-species translational neuroimaging study published in Neuropsychopharmacology, which demonstrated that ketamine suppresses the ventral striatal response to reward anticipation.
Global Versus Local Theories of Consciousness and the ... link.springer.com 2 facts
referenceThe 'reverse inference' problem in neuroimaging research refers to the practice of looking at biological signals to infer the mental states of participants.
claimWhile there is debate regarding the validity of reverse inference in neuroimaging, there is no absolute rebuttal to the idea that reverse inference is possible in principle.
(PDF) Unifying Theories of Consciousness, Attention, and ... academia.edu 1 fact
claimNeuroimaging studies using EEG, MEG, and fMRI are uncovering distinct neuronal correlates of selective attention and consciousness in dissociative paradigms, suggesting a functional dissociation where attention acts as an analyzer and consciousness acts as a synthesizer.
Psychedelics, Sociality, and Human Evolution frontiersin.org 1 fact
referenceCarhart-Harris et al. (2014) proposed 'The entropic brain' theory, which models conscious states using neuroimaging research on psychedelic drugs.
[PDF] A Consensus Taxonomy of Altered (Nonordinary) States of ... behavior-of-organisms.org 1 fact
referenceThe article titled 'A theory of conscious states informed by neuroimaging research with psychedelic drugs' is published in the journal Frontiers in Human Neuroscience as Volume 8, Article 20.