Knowledge Tree
dopamine
Also known as: DA
Facts (22)
Sources
The Difference Between The Male and Female Brain - The Renewal ... therenewalpoint.com 4 facts
claimDopamine is identified as the principal neurotransmitter in men, associated with competition, risk-taking, and motivation.
procedureThe Renewal Point treats patients by reestablishing proper serotonin and dopamine levels and calming the 'worry-center' of the brain to help patients gain a better sense of balance.
claimDepletion of dopamine in men, often caused by over-competing or over-driving, can lead to feelings of grumpiness and being in a 'grey zone'.
claimMen experiencing dopamine depletion may attempt to increase their levels by engaging in high-risk activities such as riding motorcycles, flying airplanes, driving fast sports cars, or having affairs.
“Plants of the Gods” and their hallucinogenic powers in ... surgicalneurologyint.com Jul 19, 2021 4 facts
claimCocaine acts as an indirect sympathomimetic drug that crosses the blood–brain barrier and blocks the transport of dopamine, serotonin, and norepinephrine, which inhibits the re-uptake of these neurotransmitters at presynaptic terminals and increases their quantity and receptor activation in postsynaptic neurons.
claimTHC alters mood and cognition by binding to cannabinoid receptors in the brain and potentially through the indirect release of dopamine.
claimMescaline (3,4,5-trimethoxyphenylethylamine) is the active principle in peyote and is a psychoactive phenylethylamine related to the neurotransmitters norepinephrine and dopamine, and the hormone epinephrine.
claimLSD (lysergic acid diethylamide) is a semi-synthetic hallucinogen that binds to 5-HT and dopamine receptors, acting as an agonist for both to mimic and amplify neurotransmitter properties in the central nervous system, which induces psychedelic effects.
Effects of psychedelics on neurogenesis and broader neuroplasticity link.springer.com Dec 19, 2024 4 facts
claimStandard antidepressants function primarily by targeting the monoamine neurochemical route to restore dopamine (DA), noradrenaline (NA), and serotonin (5-HT) levels to homeostatic concentrations.
claimPsychoactive tryptamines act as potent 5-HT2A agonists and often demonstrate affinity for 5-HT1 and other 5-HT2 receptors, as well as potential interactions with ionotropic and metabotropic glutamate receptors, dopamine, acetylcholine, and trace amine-associated receptors (TAAR) (Carbonaro and Gatch 2016).
claimKetamine treatment in adolescent mice induces hyperlocomotion, anxiety, ataxia, stereotyped behaviour, mitochondrial damage, and morphological abnormalities in hippocampal and cortical cells, alongside increased dopamine and glutamate levels in the cortex and hippocampus.
claimPsychoactive tryptamines interact with multiple neurotransmission systems, including serotonin, glutamate, dopamine, and sigma-1 receptors, to produce a broad spectrum of effects.
Complexity and the Evolution of Consciousness | Biological Theory link.springer.com Sep 14, 2022 4 facts
claimAlmost all vertebrates share an evaluative neural system for reward and punishment that utilizes dopamine and other valence-related molecules with a deep, ancient evolutionary origin.
claimNematodes use dopamine and other valence-related molecules to organize action and motor activity, which serves as evidence for the ancient origin of valence in helping organisms achieve efficient action selection (Barron et al. 2010).
referenceA.B. Barron, E. Søvik, and J.L. Cornish published a study in 2010 on the roles of dopamine and related compounds in reward-seeking behavior across animal phyla.
claimDopamine is at least as old as the invention of the bilaterian body plan, which enabled a vast increase in the possibilities for animal action (Caveney et al. 2006).
Neuroimaging in psychedelic drug development: past, present, and ... nature.com Sep 27, 2023 2 facts
referenceVollenweider et al. (1999) conducted a PET study using [11C]raclopride to investigate 5-HT modulation of dopamine release in the basal ganglia during psilocybin-induced psychosis in humans.
claimResearchers have evaluated the downstream effects of psilocybin using [11C]raclopride PET to measure dopamine release and [18F]fluorodeoxyglucose PET to measure changes in glycolysis and brain metabolism.
The Mechanisms of Psychedelic Visionary Experiences - Frontiers frontiersin.org Sep 27, 2017 2 facts
claimRay (2012, 2016) defines a 'mental organ' as the specific profile of effects elicited by each neurotransmitter system, including serotonin receptor subtypes, beta receptors, dopamine, histamine-1, imidazoline-1, kappa, mu, sigma, and cannabinoid receptors.
claimPsychedelics affect a variety of neurotransmitters, including serotonin, acetylcholine, norepinephrine, and dopamine.
Psychedelics, Sociality, and Human Evolution frontiersin.org 1 fact
claimThe human striatum exhibits a unique neurochemical profile involving high dopamine levels, which is consistent with the distinctive ultrasociality of humans, according to Raghanti et al. (2018).
Self-awareness, self-regulation, and self-transcendence (S-ART) frontiersin.org 1 fact
measurementPositron emission tomography (PET) data demonstrates increased endogenous dopamine release in the ventral striatum during Yoga Nidra meditation, a finding accompanied by a reported decrease in the desire for action (Kjaer et al., 2002).