Knowledge Tree
clinical trials
Also known as: clinical trials, clinical trial, Clinical trials
Facts (27)
Sources
Medicinal plants and human health: a comprehensive review of ... link.springer.com Nov 5, 2025 4 facts
claimDi Blasi et al. (2024) state that numerous medicinal plants treasured by traditional healers for centuries are currently being validated in rigorous clinical trials.
claimModern clinical trials are increasingly validating combination approaches in medicinal plant use, which mirror traditional practices where healers utilized complex formulations rather than single plants.
claimThe identification of biomarkers for therapeutic efficacy facilitates personalized medicine strategies and enhances patient stratification in clinical trials by enabling accurate assessment of treatment response, according to Shoaib et al. (2023).
procedureMethodologies for evaluating combination therapies involving phytochemicals include preclinical investigations, pharmacokinetic modeling, and meticulously structured clinical trials.
Ancient Roots of Today's Emerging Renaissance in ... link.springer.com 3 facts
claimThe development of novel pharmacologic approaches for mental health maladies has stagnated due to a growing interest in non-pharmacological treatments, a shift in funding by the National Institutes of Mental Health from clinical trials to basic research, and pharmaceutical companies prioritizing conditions with lower risks and higher profit margins, as argued by Wortzel et al. (2020), Reardon (2017), Lewis-Fernandez et al. (2016), and Miller (2010).
claimIn the last decade, governing bodies have approved clinical trials for MDMA, ketamine, LSD, psilocybin, and dimethyltryptamine.
referenceSara Reardon published 'US mental-health agency’s push for basic research has slashed support for clinical trials' in the journal Nature in 2017.
Dietary Diversity Indicators: Cultural Preferences and Health ... frontiersin.org 2 facts
claimThe Research Topic titled "Dietary Diversity Indicators: Cultural Preferences and Health Outcomes" accepts the following article types: Original Research, Systematic Review, Clinical Trial, Conceptual Analysis, and Brief Research Report.
procedureAccepted article types for the 'Dietary Diversity Indicators: Cultural Preferences and Health Outcomes' research topic include Original Research, Systematic Review, Clinical Trial, and Conceptual Analysis.
History of modern nutrition science—implications for current ... bmj.com Jun 13, 2018 2 facts
claimFuture conclusions regarding diet and health should rely on complementary evidence derived from controlled interventions of multiple surrogate endpoints, mechanistic studies, prospective observational studies, and clinical trials of disease outcomes.
claimClinical trials in nutrition science have been used to test specific questions in targeted, high-risk populations, particularly regarding the effects of isolated vitamin supplements and specific diet patterns.
Neuroimaging in psychedelic drug development: past, present, and ... nature.com Sep 27, 2023 2 facts
claimThe use of neuroimaging in clinical trials provides scientific results, informs theories of psychedelic effects, and produces visually-arresting results that are reproduced in mainstream media.
claimEarly-phase (I/IIa) clinical trials for psychedelic drugs typically utilize healthy subjects, though follow-up studies with clinical populations or inclusion of neuroscientific measures in later-phase trials are desirable.
How do the indices based on the EAT-Lancet recommendations ... medrxiv.org May 14, 2024 2 facts
claimQuantitative scoring indices are valuable tools for studies requiring precision and granularity, such as clinical trials or epidemiological studies.
claimDietary indices using quantitative scoring are advantageous in precision-focused research, such as clinical trials or epidemiological research, because they allow a global understanding of dietary health and sustainability.
The Montreal model: an integrative biomedical-psychedelic ... frontiersin.org 1 fact
referenceSeeman (2001) discussed the applicability of clinical trial results in psychiatry to real-world clinical practice.
Medicinal plants meet modern biodiversity science - OUCI ouci.dntb.gov.ua 1 fact
claimFan et al. reviewed the current status and future perspectives of Panax ginseng clinical trials.
History and Current Status of Psychedelics and Entactogens ... - NCBI ncbi.nlm.nih.gov 1 fact
procedureThe psilocybin clinical trial protocol at Johns Hopkins University for major depressive disorder includes preparatory visits with a facilitator, treatment sessions involving eyeshades and headphones with standardized music, and subsequent integrative sessions to process insights.
A virtual clinical trial of psychedelics to treat patients with disorders ... eurekalert.org Nov 24, 2025 1 fact
quote“The results of the study suggest that if this treatment was to be carried out in real clinical settings, the type of patients who would most likely benefit would be an MCS patient with a strongly connected functional connectivity. This provides a starting point to target potential future clinical trials.”
Published Studies — Johns Hopkins Center for Psychedelic and ... hopkinspsychedelic.org 1 fact
referenceThe study 'Trip sitting or just sitting? Session facilitators substantially influence psychedelic experiences in clinical trials but not in healthy ones' was published in Psychiatry Research in 2026 by Goldy, S. P., Sepeda, N. D., Hilbert, S. N., Bari, B. A., Garcia-Romeu, A., Gukasyan, N., Barrett, F. S., Yaden, D. B., and Nayak, S. M.
Vernonia amygdalina: a comprehensive review of the ... frontiersin.org 1 fact
claimFuture research on Vernonia amygdalina should clarify the mechanisms of action of important phytochemicals, conduct clinical trials to support conventional claims, investigate possible synergistic effects of compounds, and create standardized formulations for therapeutic applications.
The battle of the sexes: Whose brain comes out on top? pennneuroknow.com Dec 23, 2025 1 fact
claimThe United States Food and Drug Administration (FDA) maintained a policy that excluded women from clinical trials until the 1990s.
Altered States of Consciousness, Psychedelics - Academia.edu academia.edu 1 fact
claimVarious organizations are establishing psychedelic integration groups, available both in-person and online, with ongoing discussions regarding the necessity of providing enhanced integration services within the community following clinical trials.
A Comprehensive Review on the Therapeutic Properties of ... traditionalmedicine.actabotanica.org 1 fact
claimCurcumin has therapeutic roles that have been examined through clinical trials, as reported in a 2013 study.
Bridging the Gap Between LLMs and Evolving Medical Knowledge arxiv.org Jun 29, 2025 1 fact
claimThe AMG-RAG system leverages explicit relationships in a graph-centric retrieval process to synthesize information across domains including drug interactions, clinical trials, patient histories, and guidelines.
Self-awareness, self-regulation, and self-transcendence (S-ART) frontiersin.org 1 fact
perspectiveThe S-ART framework authors argue that the field must examine the adverse effects of long-term meditation practice, which are often overlooked in clinical trials but may be more prevalent in long-term retreats or in practitioners with predispositions toward psychopathology.
Psychedelics and disorders of consciousness - Oxford Academic academic.oup.com 1 fact
claimClinical trials are currently underway to investigate whether psychedelic substances can treat psychiatric conditions.