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The development of novel pharmacologic approaches for mental health maladies has stagnated due to a growing interest in non-pharmacological treatments, a shift in funding by the National Institutes of Mental Health from clinical trials to basic research, and pharmaceutical companies prioritizing conditions with lower risks and higher profit margins, as argued by Wortzel et al. (2020), Reardon (2017), Lewis-Fernandez et al. (2016), and Miller (2010).

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