concept

cerebrospinal fluid

Also known as: CSF

Facts (20)

Sources

Extent and Health Consequences of Chronic Sleep Loss and ... - NCBI ncbi.nlm.nih.gov Colten HR, Altevogt BM · National Academies Press 7 facts

claimSome individuals with partial hypocretin cell loss may maintain normal levels of cerebrospinal fluid (CSF) hypocretin-1, as hypothesized by Mignot et al. (2002a) and Scammell (2003).

procedureNarcolepsy can be diagnosed clinically, by using the Multiple Sleep Latency Test (MSLT), or by measuring cerebrospinal fluid (CSF) hypocretin-1.

referenceKanbayashi et al. (2002) measured cerebrospinal fluid hypocretin-1 (orexin-A) concentrations in patients with narcolepsy (with and without cataplexy) and idiopathic hypersomnia.

claimLow levels of hypocretin-1 in the cerebrospinal fluid (CSF) can be used to diagnose narcolepsy in some cases.

referenceGarrick NA et al. demonstrated in a 1983 Science publication that light and propranolol suppress the nocturnal elevation of serotonin in the cerebrospinal fluid of rhesus monkeys.

referenceKrahn et al. (2002) analyzed hypocretin (orexin) levels in the cerebrospinal fluid of patients with narcolepsy and their relationship to cataplexy and HLA DQB1*0602 status.

referenceMignot et al. (2002) established that cerebrospinal fluid hypocretin measurement is a relevant diagnostic tool for narcolepsy and other hypersomnias.

Human body systems: Overview, anatomy, functions | Kenhub kenhub.com Kenhub 4 facts

claimThe central parts of the central nervous system contain spaces called ventricles that are filled with cerebrospinal fluid.

claimThe spinal canal is filled with cerebrospinal fluid and communicates with the ventricles of the brain.

claimThe spinal cord is located within the vertebral column and contains a spinal canal that is filled with cerebrospinal fluid and communicates with the ventricles of the brain.

claimThe spinal canal extends through the central part of the spinal cord, is filled with cerebrospinal fluid, and communicates with the ventricles of the brain.

Chapter 1. Body Structure – Human Anatomy and Physiology I louis.pressbooks.pub Pressbooks 2 facts

referenceThe brain and spinal cord are protected by the bones of the skull and vertebral column, as well as by cerebrospinal fluid, a colorless fluid produced by the brain that cushions these structures within the posterior (dorsal) cavity.

claimCerebrospinal fluid is the circulatory medium within the central nervous system, produced by ependymal cells in the choroid plexus filtering the blood.

Sleep's Crucial Role in Preserving Memory | Yale School of Medicine medicine.yale.edu Yale School of Medicine May 10, 2022 2 facts

procedureThe glymphatic system operates by allowing cerebrospinal fluid to flow into spaces around arteries, passing through aquaporin-4 (AQP4) water channels into brain tissues to mix with metabolic waste, and then moving out of brain tissues into the space surrounding veins for clearance through the lymphatic or circulatory system.

procedureThe glymphatic system operates by allowing cerebrospinal fluid to flow into spaces around arteries, passing through aquaporin-4 (AQP4) water channels into brain tissues to mix with metabolic waste, and then exiting into the space surrounding veins for clearance through the lymphatic or circulatory system.

Neuroanatomy, Neuron Action Potential - StatPearls - NCBI Bookshelf ncbi.nlm.nih.gov National Library of Medicine 1 fact

procedureDiagnosis of Multiple Sclerosis (MS) can be aided by testing for oligoclonal bands of IgG in cerebrospinal fluid using electrophoresis.

Associations Between Sleep Duration and Cognitive Function ... humanfactors.jmir.org JMIR Human Factors 1 fact

referenceBoespflug and Iliff (2018) described the emerging relationship between the exchange of interstitial fluid and cerebrospinal fluid, amyloid-β levels, and sleep.

Adversarial testing of global neuronal workspace and ... - Nature nature.com Nature Apr 30, 2025 1 fact

procedureThe researchers modeled BOLD signal responses to experimental variables by fitting a voxel-wise general linear model (GLM) to each run using FSL FEAT. The model included 12 regressors of interest (targets, task-relevant, and task-irrelevant stimuli for faces, objects, letters, and false fonts) convolved with a double gamma haemodynamic response function, along with 24 motion regressors and cerebrospinal fluid (CSF) and white matter (WM) tissue regressors.

A Synergistic Workspace for Human Consciousness Revealed by ... elifesciences.org eLife 1 fact

procedureThe anatomical CompCor method for denoising functional MRI data involves regressing out the following confounding effects: the first five principal components of white matter signal, the first five principal components of cerebrospinal fluid (CSF) signal, six subject-specific realignment parameters (three translations and three rotations) plus their first-order temporal derivatives, artifacts identified by the 'art' software, and the main effect of the scanning condition.

Impact of sleep duration on executive function and brain structure nature.com Nature Mar 3, 2022 1 fact

procedureThe T1 image processing pipeline included gradient distortion correction, registration to MNI152 space, segmentation into grey matter, white matter, and cerebrospinal fluid using FMRIB’s Automated Segmentation Tool (FAST), and bias field correction.