Knowledge Tree
amygdala
Facts (35)
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Self-awareness, self-regulation, and self-transcendence (S-ART) frontiersin.org 15 facts
claimIncreased activity in the amygdala during compassion-related tasks may indicate regulatory states like equanimity, rather than contradicting traditional models of controlled emotion regulation.
referenceIn both rodents and humans, the brain areas involved in conditioning and extinguishing fear include the hippocampus, amygdala, rhinal cortices, and the ventromedial prefrontal cortex (VMPFC).
referenceBrain areas critical for their interactions with the prefrontal cortex (PFC) in emotion regulation include the amygdala, hippocampus, striatum (including the nucleus accumbens), thalamus, and insula.
measurementAdept practitioners of Zen meditation show reduced activity in executive, evaluative, and emotion-related brain areas (prefrontal cortex, amygdala, hippocampus) during acute pain compared to control subjects, according to Grant et al. (2010b).
claimThe ventromedial prefrontal cortex (VMPFC) supports the representation of affective and motivational states through a gradient of non-conscious and conscious affective appraisal by maintaining heavy interconnections with the amygdala and the ventral striatal pallidal complex, including the nucleus accumbens.
claimThe autobiographical self, defined as a set of memories comprising an individual's unique past, current state, and expected future, accumulates through interactions between the posterior medial cortex (PMC) and subcortical limbic structures such as the hippocampus and amygdala.
measurementSocial anxiety patients show a more rapid decrease in amygdala activation in response to negative self-beliefs following a Mindfulness-Based Intervention (MBI), according to Goldin and Gross (2010).
claimMental noting and labeling of emotional experience modalities is a non-cognitive strategy shown to reduce amygdala activity and emotional expression.
claimExpert meditators show increased activation in the amygdala, right temporoparietal junction (TPJ), and right posterior superior temporal sulcus (pSTS) in response to emotional human vocalizations compared to novices during compassion meditation.
referenceB. K. Holzel, J. Carmody, K. C. Evans, E. A. Hoge, J. A. Dusek, L. Morgan, et al. published a 2010 study in Social Cognitive and Affective Neuroscience finding that stress reduction correlates with structural changes in the amygdala.
measurementIncreased dispositional mindfulness, as measured by the Mindful Attention Awareness Scale (MAAS), correlates with increased activation of the ventrolateral prefrontal cortex (VLPFC) and attenuated activation in the amygdala, according to Lieberman et al. (2007).
referencePhelps et al. (2004) studied the role of the amygdala and the ventromedial prefrontal cortex (vmPFC) in human extinction learning.
claimThe ventromedial prefrontal cortex (VMPFC) modulates the amygdala response and extinguishes the expression of fear within the relevant functional circuitry.
referenceLieberman et al. (2007) demonstrated that affect labeling disrupts amygdala activity in response to affective stimuli, published in Psychological Science.
referenceStructural connectivity between the dorsolateral prefrontal cortex (DLPFC) and the amygdala is implicated in learned safety, suggesting effortful control over the expression of fear-related behavior, as reported by Pollak et al. (2010).
How men's and women's brains are different | Stanford Medicine stanmed.stanford.edu May 22, 2017 4 facts
claimBrain regions that differ in size between men and women, such as the amygdala and the hippocampus, tend to contain high concentrations of sex hormone receptors.
claimWhen adjusted for total brain size, a man's amygdala is larger than a woman's and functions differently.
accountIn a 2000 study, Larry Cahill scanned the brains of men and women viewing aversive or neutral films and found that amygdala activity predicted memory recall in the left amygdala for women and in the right amygdala for men.
claimThe amygdala is likely involved in the development of depression or anxiety.
Neuroimaging in psychedelic drug development: past, present, and ... nature.com Sep 27, 2023 4 facts
claimThe first open-label study of psilocybin for treatment-resistant depression showed that changes in cerebral blood flow in the amygdala, measured with arterial spin-labelling MRI, correlated with changes in depression scores.
claimPsilocybin therapy for treatment-resistant depression is associated with changes in amygdala and prefrontal functional connectivity during emotional processing, as reported in a 2020 study.
claimResearch on the cohort from the first open-label psilocybin study for treatment-resistant depression found increased amygdala responses to emotional stimuli, that changes in amygdala connectivity predict some clinical outcomes, and that patients show increased brain response to music stimuli following treatment.
referenceRoseman et al. (2018) observed increased amygdala responses to emotional faces in patients after receiving psilocybin for treatment-resistant depression.
The Mechanisms of Psychedelic Visionary Experiences - Frontiers frontiersin.org Sep 27, 2017 2 facts
referenceThe ventral anterior cingulate cortex (ACC) has strong connections to limbic structures (amygdala, hippocampus), cortical areas mediating limbic structures (orbitofrontal cortex and anterior insula), the periaqueductal gray, the nucleus accumbens, and the hypothalamus, giving it a central role in assessing and mediating emotionally salient stimuli, as stated by Washington and VanMeter (2015).
claimPsilocybin produces a shift in emotional biases toward positive stimuli by decreasing visual threat processing, which is achieved by reducing the modulation caused by top-down connections from the amygdala to the primary visual cortex.
Sex differences in cardiorespiratory control under hypoxia - Frontiers frontiersin.org Jan 30, 2025 1 fact
claimSex-related differences in cardiovascular autonomic modulation may be partially attributed to the effects of estrogen, oxytocin-stimulated neurons affecting vagal tone, amygdala activity, sex-related differences in brain structures, and the predominance of beta-adrenergic vasodilation in young females.
Psychedelics, Sociality, and Human Evolution frontiersin.org 1 fact
measurementHealthy subjects (n=12) experienced enhanced emotional self-control and tolerance, decreased negative mood, increased positive mood, and decreased amygdala response to negative affective stimuli after psilocybin administration, according to Barrett et al. (2020).
Psychedelics and Consciousness: Distinctions, Demarcations, and ... ouci.dntb.gov.ua 1 fact
claimLeor Roseman et al. observed increased amygdala responses to emotional faces after psilocybin treatment for treatment-resistant depression, published in Neuropharmacology, volume 142, page 263.
Ancient Roots of Today's Emerging Renaissance in ... link.springer.com 1 fact
claimClassic psychedelics initiate a cascade of altered neural connectivity and blood-flow across brain regions including the default-mode network (medial prefrontal cortex, posterior cingulate cortex, inferior parietal lobule, lateral temporal cortex, hippocampus, and precuneus), the amygdala, the thalamus, and the claustrum.
The function(s) of consciousness: an evolutionary perspective frontiersin.org Nov 25, 2024 1 fact
claimHabitat navigation is linked to olfactory centers through connections to the hippocampus, memory, and the amygdala via the orbitofrontal complex, as noted by Jacobs (2012).
Non-physicalist Theories of Consciousness cambridge.org Dec 20, 2023 1 fact
claimBrain scanning techniques such as PET and fMRI have revealed detailed correlations between specific conscious states and brain states, such as the correlation between seeing red and activity in the visual cortex, or anxiety and an overactive amygdala.
Consciousness and Cognitive Sciences journal-psychoanalysis.eu 1 fact
claimRecent research indicates that the separation between reasoning and emotions is disappearing, with evidence highlighting the importance of the amygdala, the lateralization of emotional processes, and the role of arousal in emotional memory.
Is There a Male Brain and a Female Brain? | Child & Family Blog childandfamilyblog.com 1 fact
measurementSex/gender differences in the size of the hippocampus and the amygdala are no more than 1%.
GWT: A Leading Consciousness Theory Depends on Information ... mindmatters.ai Oct 15, 2021 1 fact
referenceMorten L. Kringelbach and Gustavo Deco identify the global workspace as a core subset of brain regions including the precuneus, the posterior and isthmus cingulate, nucleus accumbens, putamen, hippocampus, and amygdala.
Hard Problem of Consciousness | Internet Encyclopedia of Philosophy iep.utm.edu 1 fact
claimEpiphenomenalism posits that while bodily damage may cause activity in the amygdala and subsequent pain-appropriate behavior, the phenomenal pain properties themselves are causally inert, similar to the activity of a steam whistle relative to the causal power of a steam engine.