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Lin et al. reported that microRNA-302s can convert skin cancer cells into iPSCs, resulting in decreased tumorigenicity and genomic demethylation, with these pluripotent cancer cells displaying more than 86% gene expression similarity to human embryonic stem cell (ESC) lines.
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Sources
- Cellular rejuvenation: molecular mechanisms and potential ... - Nature www.nature.com via serper
Referenced by nodes (2)
- induced pluripotent stem cells concept
- human embryonic stem cells concept