Senescence-associated secretory phenotype (SASP) can contribute to angiogenesis, facilitate tumor development, induce epithelial-mesenchymal transition (EMT) in neighboring cancer cells, and induce extracellular matrix (ECM) degradation, which results in the migration and metastasis of cancer cells.

Authors

• Person: Not available Organization: Nature
  Cellular rejuvenation: molecular mechanisms and potential ... - Nature

Sources

• Cellular rejuvenation: molecular mechanisms and potential ... - Nature www.nature.com Nature via serper

Referenced by nodes (3)

• cancer cells concept
• extracellular matrix concept
• senescence-associated secretory phenotype concept