Drugs targeting senescence-associated secretory phenotype (SASP), such as glucocorticoids, resveratrol, and protease inhibitors, attenuate chronic kidney disease (CKD) primarily by inhibiting NF-κB signals and reducing reactive oxygen species (ROS).

Authors

• Person: Not available Organization: Nature
  Cellular rejuvenation: molecular mechanisms and potential ... - Nature

Sources

• Cellular rejuvenation: molecular mechanisms and potential ... - Nature www.nature.com Nature via serper

Referenced by nodes (3)

• NF-κB concept
• chronic kidney disease concept
• senescence-associated secretory phenotype concept