Individuals with narcolepsy with cataplexy experience severe neuronal loss in brain regions responsible for regulating the sleep-wake cycle, specifically losing approximately 70,000 hypothalamic neurons that produce the neuropeptide hypocretin (orexin).

Authors

• Person: Colten HR, Altevogt BM Organization: National Academies Press
  Extent and Health Consequences of Chronic Sleep Loss and ... - NCBI

Sources

• Extent and Health Consequences of Chronic Sleep Loss and ... - NCBI www.ncbi.nlm.nih.gov Colten HR, Altevogt BM · National Academies Press via serper

Referenced by nodes (3)

• narcolepsy concept
• Cataplexy concept
• hypocretin concept