A single period of OSKM expression in naturally aged mice alters epigenetics, transcriptomes, and metabolomes, resulting in a younger configuration in various tissues and serum, including the reversal of DNA methylation and transcriptional changes and the restoration of aging-related serum metabolites and biomarkers to youthful levels.

Authors

• Person: Not available Organization: Nature
  Cellular rejuvenation: molecular mechanisms and potential ... - Nature

Sources

• Cellular rejuvenation: molecular mechanisms and potential ... - Nature www.nature.com Nature via serper

Referenced by nodes (4)

• DNA methylation concept
• transcriptomics concept
• Epigenetics concept
• OSKM concept