Knowledge Tree
Epigenetics
Facts (14)
Sources
Cellular rejuvenation: molecular mechanisms and potential ... - Nature nature.com Mar 14, 2023 6 facts
claimAverbeck and Rodriguez-Lafrasse (2021) describe the role of mitochondria in radiation responses, specifically noting impacts on epigenetics, metabolism, and signaling.
referenceInflammation, epigenetics, and metabolism converge to influence cell senescence and aging, as described by Zhu et al. in a 2021 Signal Transduction and Targeted Therapy paper.
claimA single period of OSKM expression in naturally aged mice alters epigenetics, transcriptomes, and metabolomes, resulting in a younger configuration in various tissues and serum, including the reversal of DNA methylation and transcriptional changes and the restoration of aging-related serum metabolites and biomarkers to youthful levels.
claimSharma, Pasala, and Prakash (2019) examine the relationship between mitochondrial DNA, epigenetics, and environmental factors.
referenceThe relationship between epigenetics and aging is reviewed in the 2013 paper 'Epigenetics and aging' published in Maturitas.
referenceZhang and Ren (2016) examined the relationship between epigenetics and obesity cardiomyopathy, covering aspects from pathophysiology to prevention and management strategies.
Mitochondria and the dynamic control of stem cell homeostasis link.springer.com Apr 16, 2018 4 facts
claimMitochondria play an active role in shaping cellular fate through the modulation of bioenergetics, redox balance, calcium balance, and epigenetics.
referenceCyr et al. (2013) described the regulation of SOD2 in cancer through histone modifications and CpG methylation, linking redox biology and epigenetics.
referenceGrzybek et al. (2017) explored the epigenetics of cell fate reprogramming and its implications for modeling neurological disorders.
referenceYun et al. (2012) reviewed the interactions between epigenetics and metabolism in cancers.
Cellular senescence: from homeostasis to pathological implications ... frontiersin.org 1 fact
referenceNutrigenetics and epigenetics are linked to gestational diabetes and have consequences for both mother and child, according to Franzago et al. (2019).
Industry-Based Misconceptions Regarding Cross-Pollination of ... frontiersin.org Jan 25, 2022 1 fact
claimEpigenetics, characterized by histone modifications and DNA methylation, can alter the expression of stress-responsive genes and influence cannabinoid production in plants.
5.1 Physical Health and Growth in Early Childhood - OpenStax openstax.org Oct 16, 2024 1 fact
referenceLang et al. (2019) conducted a systematic review of the literature regarding the relationship between adverse childhood experiences, epigenetics, and telomere length variation in childhood and beyond.
Research reveals devastating impact of Western diet on human health news-medical.net Jun 18, 2023 1 fact
claimThe Western diet alters epigenetics and gene expression through mechanisms including changes in nutrient availability, hormonal levels, the supply of cofactors for gene expression, transcription factors, cellular signaling pathways, and deoxyribonucleic acid (DNA) methylation, as well as inter- and transgenerational effects.