schizophrenia ↔ psilocybin

Relations (1)

related 0.20 — supporting 2 facts

Psilocybin is related to schizophrenia as it induces schizophrenia-like psychosis in humans via serotonin-2 agonist action [1], and studies show its effects on cognitive deficits mirror those in schizophrenia, with implications for neuropharmacology [2].

Facts (2)

Sources

Psychedelics and Consciousness: Distinctions, Demarcations, and ... ouci.dntb.gov.ua David B Yaden, Matthew W Johnson, Roland R Griffiths, Manoj K Doss, Albert Garcia-Romeu, Sandeep Nayak, Natalie Gukasyan, Brian N Mathur, Frederick S Barrett · Oxford University Press 1 fact

referenceUmbricht et al. published a study in Neuropsychopharmacology titled 'Effects of the 5-HT2A agonist psilocybin on mismatch negativity generation and AX-continuous performance task: implications for the neuropharmacology of cognitive deficits in schizophrenia,' which investigates the effects of psilocybin on cognitive tasks.

Neuroimaging in psychedelic drug development: past, present, and ... nature.com Nature 1 fact

referenceF.X. Vollenweider, M.F.I. Vollenweider-Scherpenhuyzen, A. Bäbler, H. Vogel, and D. Hell published 'Psilocybin induces schizophrenia-like psychosis in humans via a serotonin-2 agonist action' in NeuroReport in 1998.