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leptin ↔ obesity

Relations (1)

related 2.00 — strongly supporting 3 facts

Leptin is an appetite-suppressing hormone whose levels are linked to obesity through dietary patterns [1] and hormonal imbalances caused by sleep deprivation [2], [3].

Facts (3)

Sources
Long-Term Effects of Chronic Sleep Deprivation empowersleep.com Empower Sleep 1 fact
claimChronic sleep deprivation increases the risk of obesity and weight gain by disrupting the balance of appetite-regulating hormones leptin and ghrelin, which leads to increased hunger and food consumption.
Western pattern diet - Wikipedia en.wikipedia.org Wikipedia 1 fact
claimThe Western pattern diet is positively correlated with plasma biomarkers that may mediate obesity, specifically HDL cholesterol, high levels of fasting insulin, and leptin.
Extent and Health Consequences of Chronic Sleep Loss and ... - NCBI ncbi.nlm.nih.gov Colten HR, Altevogt BM · National Academies Press 1 fact
claimSleep insufficiency is associated with lower levels of leptin (an appetite-suppressing hormone produced by adipose tissue) and higher levels of ghrelin (a peptide that stimulates appetite), which suggests a hormonally mediated increase in appetite explains the link between short sleep and obesity (Taheri et al., 2004).