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Relations (1)
related 2.81 — strongly supporting 6 facts
The anterior cingulate cortex is a primary node and key hub of the default mode network, as evidenced by its role in functional connectivity studies [1], [2], and [3], as well as its involvement in the network's metabolic and activity-based fluctuations [4], [5], and [6].
Facts (6)
Sources
The Mechanisms of Psychedelic Visionary Experiences - Frontiers frontiersin.org 6 facts
referenceThe anterior cingulate cortex (ACC) provides a locus for the interaction between the default mode network (DMN) and the mirror neuron system (MNS), as reported by Uddin et al. (2007).
claimEgoless experiences, measured as 'oceanic boundlessness,' are associated with alterations in the frontolimbic-parieto-striatal network and are positively correlated with cerebral glucose metabolism in Default Mode Network regions (anterior cingulate cortex, hippocampus, inferior parietal cortex) and prefrontal cortex areas (frontomedial superior, frontolateral, and left inferolateral).
claimEpileptic seizures, including complex partial, generalized tonic-clonic, and absence seizures, impair primary nodes of the Default Mode Network (DMN), specifically the precuneus/PCC, medial frontal cortex, lateral parietal cortex, and the anterior cingulate cortex (ACC), resulting in long-lasting decreases in DMN activity.
referenceThe 2016 review by dos Santos et al. reported a decrease in functional connectivity between key hubs of the Default Mode Network (DMN), specifically noting a reduction in connectivity between the posterior cingulate cortex (PCC) and the anterior cingulate cortex (ACC).
referenceHigh-hypnotizability subjects exhibit greater decreases in Default Mode Network (DMN) activity, particularly in the dorsal anterior cingulate cortex (ACC), and reduced connectivity between the posterior cingulate cortex (PCC) and the Executive Control Network, according to a 2017 study by Jiang et al.
referenceWashington and VanMeter (2015) characterized the connectivity between the dorsal and ventral regions of the medial prefrontal cortex (mPFC) and the dorsal and ventral areas of the anterior cingulate cortex (ACC) as the most anterior area of functional connectivity within the default mode network (DMN).