Relations (1)

related 2.81 — strongly supporting 6 facts

Research indicates that sleep duration has a significant quadratic relationship with the volume of the orbitofrontal cortex [1], [2], with studies showing that both shorter [3], [4] and non-optimal sleep durations [5], [6] are associated with smaller volumes in this brain region.

Facts (6)

Sources
Impact of sleep duration on executive function and brain structure nature.com Nature 6 facts
measurementVolume in 56 brain regions significantly predicted executive function, while volume in 46 brain regions showed a significant quadratic relationship with sleep duration; 41 of these brain regions overlapped, including the hippocampi, thalami, orbitofrontal cortex, right frontal pole, left parahippocampal gyri, and cerebellar regions.
claimForty-one brain regions, including the hippocampi, thalami, orbitofrontal cortex, right frontal pole, left parahippocampal gyri, and cerebellar regions, showed both a significant quadratic relationship with sleep duration and predictive power for executive function.
measurementIn a study of 37,553 UK Biobank participants, 46 brain regions were significantly larger in volume in individuals who slept between six and eight hours compared to those with other sleep durations, including the orbital frontal cortex, pre-and post-central gyri, right frontal pole, hippocampi, and thalami.
claimA whole-brain study identified that longer sleep duration is associated with a thinner cortex in the left inferior occipital gyrus, while shorter sleep duration is associated with a smaller orbitofrontal cortex and precuneus.
claimA whole brain approach study identified that shorter sleep duration is related to a smaller orbitofrontal cortex and precuneus.
claimWhen comparing individuals sleeping six to eight hours against those sleeping less than six hours, the six-to-eight hour group had larger volumes in seven regions: the orbitofrontal cortex and precentral gyrus bilaterally, the right frontal pole, the right posterior cingulate, and the right amygdala.