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PET is utilized as a neuroimaging technique to evaluate the physiological effects of psilocybin, specifically measuring dopamine release and metabolic changes as described in [1] and [2].

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Neuroimaging in psychedelic drug development: past, present, and ... nature.com Nature 1 fact

claimResearchers have evaluated the downstream effects of psilocybin using [11C]raclopride PET to measure dopamine release and [18F]fluorodeoxyglucose PET to measure changes in glycolysis and brain metabolism.

Psychedelics and Consciousness: Distinctions, Demarcations, and ... ouci.dntb.gov.ua David B Yaden, Matthew W Johnson, Roland R Griffiths, Manoj K Doss, Albert Garcia-Romeu, Sandeep Nayak, Natalie Gukasyan, Brian N Mathur, Frederick S Barrett · Oxford University Press 1 fact

referenceVollenweider et al. published 'Positron emission tomography and fluorodeoxyglucose studies of metabolic hyperfrontality and psychopathology in the psilocybin model of psychosis' in Neuropsychopharmacology, which utilizes PET and FDG to study the psilocybin model of psychosis.