Knowledge Tree
Relations (1)
related 2.00 — strongly supporting 3 facts
Psilocybin is related to the default mode network because research has demonstrated that the substance alters the network's functional connectivity [1] and reduces its oscillatory activity and power [2]. This reduction in activity is specifically attributed to decreased functional coupling between key components of the default mode network [3].
Facts (3)
Sources
The Mechanisms of Psychedelic Visionary Experiences - Frontiers frontiersin.org 2 facts
claimThe reduction in oscillatory activity and power in the Default Mode Network caused by psilocybin results from decreased functional coupling between the frontal cortex and the medial temporal lobe components of the Default Mode Network, as well as between the medial prefrontal cortex and the posterior cingulate cortex.
measurementMuthukumaraswamy et al. (2013) found that psilocybin caused a reduction in oscillatory activity and power in posterior and frontal association cortices and the Default Mode Network.
Published Studies — Johns Hopkins Center for Psychedelic and ... hopkinspsychedelic.org 1 fact
referenceA 2017 study by Barrett, Johnson, and Griffiths published in Drug and Alcohol Dependence examined the effects of psilocybin on long-term meditators, specifically regarding default mode network functional connectivity and retrospective ratings of qualitative experience.