Knowledge Tree
Type 2 Diabetes Mellitus
Also known as: type II diabetes mellitus, T2DM
Facts (23)
Sources
Short- and long-term health consequences of sleep disruption dovepress.com May 19, 2017 9 facts
claimLarge longitudinal studies have shown that sleep disruption is associated with an increased risk of developing Type 2 Diabetes Mellitus (T2DM).
referenceThe MONICA/KORA Augsburg Cohort Study (2005) identified sleep disturbance as a predictor of type 2 diabetes mellitus in men and women from the general population, published in Diabetologia.
measurementA meta-analysis of four longitudinal studies found that the overall relative risk of developing Type 2 Diabetes Mellitus (T2DM) was 1.84 (95% CI, 1.39–2.43; P < 0.0001) in adults who experienced difficulty maintaining sleep.
claimLong-term consequences of sleep disruption in otherwise healthy individuals include hypertension, dyslipidemia, cardiovascular disease, weight gain, metabolic syndrome, and type 2 diabetes mellitus.
claimLong-term consequences of sleep disruption in otherwise healthy individuals include hypertension, dyslipidemia, cardiovascular disease (CVD), weight-related issues, metabolic syndrome, and type 2 diabetes mellitus (T2DM).
measurementIn an experimental study of healthy young adults, sleep disruption characterized by three nights of slow-wave sleep (SWS) suppression resulted in decreased insulin sensitivity and reduced glucose tolerance, similar to populations at high risk of Type 2 Diabetes Mellitus (T2DM).
claimSuppression of slow-wave sleep (SWS) is associated with decreased insulin sensitivity without an increase in insulin release, which may explain the increased risk of type 2 diabetes mellitus in patients with poor sleep quality.
claimLong-term consequences of sleep disruption in otherwise healthy individuals include hypertension, dyslipidemia, cardiovascular disease, weight-related issues, metabolic syndrome, type 2 diabetes mellitus, and colorectal cancer.
referenceA review by Cedernaes et al. describes various molecular and behavioral factors that link sleep disruption to metabolic disorders, including obesity and type 2 diabetes mellitus (T2DM).
Diet Quality Indices: Measures for Bridging Nutrition and Public Health link.springer.com 2 days ago 2 facts
Physiology, Sleep Stages - StatPearls - NCBI Bookshelf - NIH ncbi.nlm.nih.gov 1 fact
claimContinuous positive airway pressure (CPAP) therapy in patients with obstructive sleep apnea and type 2 diabetes mellitus was the subject of a systematic review and meta-analysis published in the Clinical Respiratory Journal in August 2018.
Sleep Across the Lifespan: A Neurobehavioral Perspective link.springer.com Feb 5, 2025 1 fact
referenceKarthikeyan et al. (2019) discussed the contribution of the modern 24-hour society to the development of type 2 diabetes mellitus, specifically focusing on the role of insufficient sleep, published in Sleep Science.
Medicinal plants and human health: a comprehensive review of ... link.springer.com Nov 5, 2025 1 fact
referenceObakiro et al. (2025) investigated the molecular mechanisms of aloe-emodin in managing type II diabetes mellitus using network pharmacology, molecular docking, and molecular dynamics simulation approaches.
Global dietary quality in 185 countries from 1990 to 2018 show wide ... nature.com Sep 19, 2022 1 fact
referenceA 2018 study by Chen et al. published in the American Journal of Epidemiology investigated the association between diet quality indices and the risk of type 2 diabetes mellitus within the Singapore Chinese Health Study.
Immunity In Depth | Linus Pauling Institute lpi.oregonstate.edu 1 fact
claimObesity is associated with an increased risk of morbidity from chronic diseases, including hypertension, cardiovascular disease, type 2 diabetes mellitus, liver and gallbladder disease, osteoarthritis, sleep apnea, and certain cancers.
Health and environmental impacts of diets worldwide globalnutritionreport.org 1 fact
referenceSchwingshackl L, Hoffmann G, Lampousi AM, et al. performed a systematic review and meta-analysis of prospective studies regarding food groups and the risk of type 2 diabetes mellitus, published in the European Journal of Epidemiology in 2017.
Pharmacological Uses of New Bioactive Compounds from Medicinal ... academia.edu 1 fact
referenceBiswas, Behera, and Madhu reviewed the status and future prospects of technology in the management of Type 1 and Type 2 Diabetes Mellitus in 2023.
Extent and Health Consequences of Chronic Sleep Loss and ... - NCBI ncbi.nlm.nih.gov 1 fact
referenceA 25-year follow-up study by Martin et al. published in The Lancet in 1992 examined the role of glucose and insulin resistance in the development of type 2 diabetes mellitus.
Measurement of diets that are healthy, environmentally sustainable ... frontiersin.org 1 fact
claimHuman health and nutrition outcome metrics in research have expanded from a focus on mortality from cardiovascular disease and cancer to include deaths avoided from type 2 diabetes mellitus and the prevalence of serum retinol deficiency.
Chronic inflammation in the etiology of disease across the life span nature.com Dec 5, 2019 1 fact
referenceChronic inflammatory disorders are associated with an increased risk of type 2 diabetes mellitus, coronary heart disease, and stroke.
Associations between dietary diversity and self-rated health in a ... link.springer.com Feb 28, 2025 1 fact
referenceJ.W. Noh, Y. Chang, M. Park, Y.D. Kwon, and S. Ryu published the cohort study 'Self-rated health and the risk of incident type 2 diabetes mellitus: a cohort study' in Scientific Reports in 2019 (Volume 9, Issue 1, article 3697).
Chronic Inflammation - StatPearls - NCBI Bookshelf ncbi.nlm.nih.gov 1 fact
claimDiets with a high glycemic index are related to a high risk of stroke, coronary heart disease, and type 2 diabetes mellitus.