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Sleep Heart Health Study

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Extent and Health Consequences of Chronic Sleep Loss and ... - NCBI ncbi.nlm.nih.gov Colten HR, Altevogt BM · National Academies Press 24 facts

claimThe association between sleep loss and diabetes is independent of obesity, as adjustment for waist girth did not alter the significance of the findings in the Sleep Heart Health Study.

claimThe fact that adjusting for hypertension in the Sleep Heart Health Study did not eliminate the association between obstructive sleep apnea and cardiovascular disease suggests that hypertension is not the exclusive mechanism by which obstructive sleep apnea leads to cardiovascular disease.

referenceYoung T, Shahar E, Nieto FJ, Redline S, Newman AB, Gottlieb DJ, Walsleben JA, Finn L, Enright P, and Samet JM authored 'Predictors of sleep-disordered breathing in community-dwelling adults: The Sleep Heart Health Study,' published in the Archives of Internal Medicine in 2002.

claimThe Sleep Heart Health Study found a cross-sectional association between sleep-disordered breathing and cardiovascular disease.

referenceThe Sleep Heart Health Study, published by Shahar et al. in the American Journal of Respiratory and Critical Care Medicine in 2001, examined the relationship between sleep-disordered breathing and cardiovascular disease.

claimNieto et al. (2000) identified an association between sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study known as the Sleep Heart Health Study.

claimAdults with sleep times of 9 hours or more showed increased likelihood of diabetes and impaired glucose tolerance in the Sleep Heart Health Study, a finding consistent with the Nurses Health Study (Gottlieb et al., 2005).

measurementA large population-based study of more than 1,000 adults found a U-shaped relationship between sleep duration (measured by polysomnography) and body mass index, where adults who slept 7.7 hours had the lowest BMI, and those with shorter or longer sleep durations had progressively higher BMI.

measurementIn the Sleep Heart Health Study, outcomes of impaired glucose tolerance and insulin resistance were more prevalent in individuals with the highest apnea-hypopnea index.

referenceThe Sleep Heart Health Study is a community-based multicenter study of more than 6,000 middle-aged and older adults that measured the apnea-hypopnea index via polysomnography and found that the likelihood of hypertension was greater at higher apnea-hypopnea index levels.

claimThe Sleep Heart Health Study, conducted by Punjabi et al. (2004), found that sleep-disordered breathing is associated with glucose intolerance and insulin resistance.

measurementIn the Sleep Heart Health Study, participants in the highest apnea-hypopnea index quartile had an adjusted odds ratio of 1.58 (95% CI, 1.02–2.46) for stroke.

claimThe Sleep Heart Health Study identified a relationship between sleep-related hypoxemia and glucose intolerance.

claimThe association between sleep duration and diabetes in the Sleep Heart Health Study remained significant after adjusting for waist girth, suggesting the effect is independent of obesity (Gottlieb et al., 2005).

claimObstructive sleep apnea (OSA) is associated with impaired glucose tolerance and insulin resistance, according to data from studies including the Sleep Heart Health Study (Ip et al., 2002; Punjabi et al., 2002; Punjabi et al., 2004).

claimShahar E, Whitney CW, Redline S, Lee ET, Newman AB, Javier Nieto F, O'Connor GT, Boland LL, Schwartz JE, and Samet JM identified a cross-sectional association between sleep-disordered breathing and cardiovascular disease in the Sleep Heart Health Study.

measurementThe Sleep Heart Health Study, a cross-sectional study of nearly 6,500 participants, found that individuals in the highest apnea-hypopnea index quartile (index greater than 11) were 42 percent more likely to self-report cardiovascular disease, including coronary heart disease, heart failure, or stroke, compared to those in the lowest quartile (adjusted OR = 1.42, 95% CI, 1.13–1.78).

claimThe diabetes effect associated with sleep duration is independent of obesity, as adjustment for waist girth did not alter the significance of the findings in the Sleep Heart Health Study (Gottlieb et al., 2005).

measurementIn the Sleep Heart Health Study, middle-aged and older adults who reported 6 hours of sleep per night were about 1.7 times more likely to have diabetes compared to those who slept 7 to 8 hours per night.

referenceThe Sleep Heart Health Study, a large, cross-sectional, community-based study using polysomnography, found that impaired glucose tolerance and insulin resistance were more prevalent in individuals with the highest apnea-hypopnea index.

claimThe Sleep Heart Health Study determined the apnea-hypopnea index using polysomnography and adjusted for confounding factors, including hypertension, finding that the association between obstructive sleep apnea and cardiovascular disease persisted even after adjusting for hypertension.

claimThe Sleep Heart Health Study, published in the Journal of the American Medical Association in 2000, found an association between sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study.

measurementIn the Sleep Heart Health Study, middle-aged and older adults who reported 5 hours of sleep or less were 2.5 times more likely to have diabetes compared to those who slept 7 to 8 hours per night.