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Quercetin
Facts (23)
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Medicinal plants and human health: a comprehensive review of ... link.springer.com Nov 5, 2025 10 facts
claimResveratrol from red grapes, berberine from goldenseal, and quercetin from onions facilitate Th1 responses to augment cellular immunity while inhibiting excessive Th2 responses linked to allergic reactions.
measurementQuercetin competitively suppresses HIV-1 reverse transcriptase with a Ki of 12 μM by interacting with the enzyme’s primer grip region.
referenceSun et al. (2024) demonstrated that quercetin protects blood–brain barrier integrity via the PI3K/Akt/Erk signaling pathway in a mouse model of meningitis induced by Glaesserella parasuis.
measurementQuercetin derived from Allium cepa inhibits bacterial DNA gyrase with an IC50 of 15 μg/mL and also inhibits topoisomerase IV, which are critical enzymes for bacterial DNA replication.
referenceQuercetin from onions, tannic acid from tea, and rosmarinic acid from rosemary function by directly attaching to amyloid proteins and augmenting microglial phagocytosis, according to Ştefănescu (2025).
measurementQuercetin at dosages of 25–50 μM enhances tight junction protein expression by 40–60% in brain endothelial cell models, and anthocyanins exhibit comparable protective benefits in vivo.
claimFlavonoids, including quercetin from onions and apples, rutin from buckwheat, and anthocyanins from blueberries and blackberries, bolster blood–brain barrier integrity by fortifying tight junction proteins and diminishing oxidative stress-induced permeability.
referenceR. Dhanya (2022) explores the use of quercetin for managing type 2 diabetes and its complications through multitarget therapy in Biomedicine & Pharmacotherapy.
claimQuercetin and flavonoid chemicals derived from onions augment peripheral glucose uptake and increase the translocation of glucose transporters, enhancing cellular glucose consumption and providing mechanisms for postprandial glucose regulation through improved insulin sensitivity.
referenceA. Di Petrillo et al. (2022) provide a comprehensive review of quercetin and its derivatives as potential antiviral agents in Phytotherapy Research.
Medicinal plants: bioactive compounds, biological activities ... frontiersin.org 5 facts
claimCompounds such as resveratrol and quercetin inhibit the expression of genes that encode virulence factors.
claimHoney flavonoids and quercetin impede the growth of Candida albicans by increasing intracellular reactive oxygen species levels.
claimFlavonoids including quercetin and apigenin, and phenolic acids including ellagic acid and caffeic acid, impede biofilm formation in Candida species, including the drug-resistant Candida auris.
claimFlavonoids, including quercetin and apigenin, inhibit the production of peptidoglycan, which is an essential component of the bacterial cell wall.
claimFlavonoids such as quercetin, apigenin, and sakuranetin from Plukenetia volubilis leaves act as antimicrobials by blocking bacterial fatty acid biosynthesis enzymes in Helicobacter pylori.
Pharmacological Uses of New Bioactive Compounds from Medicinal ... academia.edu 4 facts
referenceQuercetin and rutin function as a dual approach to antibacterial and anti-biofilm activity through an iron chelation mechanism, as reported by Carbone, Mashhoud, and Tahan in 2024.
referenceQuercetin exhibits anti-cancer effects, and research by Tang et al. (2019) provides a pharmacological basis and new insights into these mechanisms.
claimNair et al. (2006) found that the flavonoid Quercetin inhibits proinflammatory cytokine (Tumor Necrosis Factor Alpha) gene expression in normal peripheral blood mononuclear cells by modulating the NF-κβ system.
claimQuercetin is reviewed as a potential treatment for hypertension, with an analysis of its efficacy and mechanism provided by Larson, A., Symons, J. D., and Jalili, T. in 2010.
Pharmacological Uses of New Bioactive Compounds from Medicinal ... ouci.dntb.gov.ua 2 facts
referenceAghababaei, F. and Hadidi, M. published a review titled 'Recent Advances in Potential Health Benefits of Quercetin' in the journal Pharmaceuticals in 2023.
claimThe flavonoid quercetin inhibits the gene expression of the proinflammatory cytokine tumor necrosis factor alpha in normal peripheral blood mononuclear cells by modulating the NF-κβ system.
Investigation of nutritional and phytochemical properties of wild ... nature.com Dec 9, 2025 1 fact
claimThe phenolic acids and flavonoids analyzed via UPLC-PDA include P-coumaric acid, Gallic acid, Pro-catechuic acid, Vanillic acid, Rutin, Syringic acid, Caffeic acid, Epicatechin, EGCG, Ferulic acid, Quercetin, and Kaempferol.
Phytochemical and Pharmacological Studies of Traditionally Used ... heraldopenaccess.us 1 fact
claimSilybum marianum contains the flavonoid compounds taxifolin, dihydrokaempferol, and quercetin.