concept

N, N-dimethyltryptamine

Also known as: DMT

Facts (17)

Sources
Psychedelics and Consciousness: Distinctions, Demarcations, and ... ouci.dntb.gov.ua David B Yaden, Matthew W Johnson, Roland R Griffiths, Manoj K Doss, Albert Garcia-Romeu, Sandeep Nayak, Natalie Gukasyan, Brian N Mathur, Frederick S Barrett · Oxford University Press 4 facts
measurementLSD induces significantly more inositol phosphate formation at the 5-HT2A receptor than DMT and psilocin.
claimRoland Griffiths conducted a survey comparing naturally occurring 'God encounter experiences' with those occasioned by classic psychedelics including psilocybin, LSD, ayahuasca, or DMT.
claimThe literature regarding neural fingerprints of DMT, LSD, and psilocybin is characterized by high heterogeneity and a risk of bias, creating an urgent need for standardized experimental procedures and analysis techniques.
claimMeta-analyses link DMT, LSD, and psilocybin to specific neural fingerprints at each level of analysis, revealing a highly non-linear relationship between these fingerprints.
Effects of psychedelics on neurogenesis and broader neuroplasticity link.springer.com Springer Dec 19, 2024 4 facts
referenceBrito-da-Costa et al. (2020) analyzed the toxicokinetics and toxicodynamics of Ayahuasca alkaloids, specifically N,N-Dimethyltryptamine (DMT), Harmine, Harmaline, and Tetrahydroharmine.
claimThe hallucinogen N,N-dimethyltryptamine (DMT) functions as an endogenous sigma-1 receptor regulator.
referenceMorales-Garcia et al. (2020) published a study in Translational Psychiatry reporting that N,N-dimethyltryptamine (DMT), a compound found in the hallucinogenic tea Ayahuasca, regulates adult neurogenesis both in vitro and in vivo.
referenceCarbonaro TM and Gatch MB published 'Neuropharmacology of N,N-Dimethyltryptamine' in 'Brain Research Bulletin' in 2016.
Published Studies — Johns Hopkins Center for Psychedelic and ... hopkinspsychedelic.org Johns Hopkins Center for Psychedelic and Consciousness Research 2 facts
referenceA survey of entity encounter experiences occasioned by inhaled N,N-dimethyltryptamine (DMT) examined the phenomenology, interpretation, and enduring effects of these experiences.
referenceLawrence, B. W., Carhart-Harris, R., Griffiths, R. R., and Timmermann, C. published a study in Scientific Reports in 2022 on the phenomenology and content of the inhaled N, N-dimethyltryptamine (N, N-DMT) experience.
The Mechanisms of Psychedelic Visionary Experiences - Frontiers frontiersin.org Frontiers Sep 27, 2017 1 fact
referenceThe paper 'Dose-response study of N,N-dimethyltryptamine in humans. II. Subjective effects and preliminary results of a new rating scale' by R. Strassman, C. Qualis, E. Uhlenhuth, and R. Kellner, published in Archives of General Psychiatry in 1994, reports on the effects of DMT.
A Synergistic Workspace for Human Consciousness Revealed by ... elifesciences.org eLife 1 fact
referenceThe study 'Human brain effects of DMT assessed via EEG-fMRI' published in the Proceedings of the National Academy of Sciences assesses the effects of DMT on the human brain using EEG-fMRI.
Theories and Methods of Consciousness biomedres.us Paul C Mocombe · Biomedical Journal of Scientific & Technical Research Jan 29, 2024 1 fact
referenceTimmermann C, Roseman L, Williams L, Erritzoe D, Martial C, et al. published 'DMT Models the Near-Death Experience' in Frontiers in Psychology in 2018.
Classification Schemes of Altered States of Consciousness - ORBi orbi.uliege.be ORBi 1 fact
referenceTimmermann et al. published research on the effects of DMT on mental health outcomes in healthy volunteers in Scientific Reports in 2024.
Psychedelics, Sociality, and Human Evolution frontiersin.org Frontiers 1 fact
referenceDavis et al. (2020) conducted a survey on the phenomenology, interpretation, and enduring effects of entity encounter experiences occasioned by inhaled N,N-dimethyltryptamine (DMT), published in the Journal of Psychopharmacology.
The Montreal model: an integrative biomedical-psychedelic ... frontiersin.org Frontiers in Psychiatry 1 fact
claimN,N-Dimethyltryptamine (DMT) and nitrous oxide are short-acting psychedelic-like drugs that may be employed in therapeutic models similar to the Montreal model of ketamine administration.
Neuroimaging in psychedelic drug development: past, present, and ... nature.com Nature Sep 27, 2023 1 fact
claimModern research into classic psychedelics and related compounds includes the study of LSD, psilocybin, N,N-Dimethyltryptamine (DMT), MDMA, ketamine, and ibogaine.