Knowledge Tree
Luteolin
Facts (15)
Sources
Vernonia amygdalina: a comprehensive review of the ... frontiersin.org 8 facts
measurementLuteolin exhibits antioxidant activity with a 49% DPPH radical scavenging potential.
claimLuteolin, isorhamnetin, 6β,10β,14β-Trimethylheptadecan-15α-olyl-15-O-β-D-glucopyranosyl1,5β-olide, 1-Heneicosenol O-β-D-glucopyranoside, 11α-Hydroxyurs-5,12-dien-28-oic acid-3α,25-olide, 10-Geranilanyl-O-β-D-xyloside, and Glucuronolactone exhibit antioxidant efficacy.
referenceDjeujo, F. M., Stablum, V., Pangrazzi, E., Ragazzi, E., and Froldi, G. published a study on the effects of luteolin and vernodalol from Vernonia amygdalina leaf and root extracts on α-glucosidase, glycation, ROS, cell viability, and in silico ADMET parameters in Pharmaceutics in 2023.
claimLuteolin has been isolated from the leaves of Vernonia amygdalina, and Vernodalol has been isolated from the roots of Vernonia amygdalina, as reported by Djeujo et al. (2023).
claimLuteolin is considered safe and possesses adequate pharmacokinetic characteristics.
claimLuteolin demonstrates antioxidant and anti-cancer properties, indicated by its capacity to scavenge free radicals and decrease HT-29 cell viability with an IC50 of 22.2 µM.
claimCompounds isolated from Vernonia amygdalina include vernolide, luteolin, vernodalol, vernoamyoside A, vernoamyoside B, isorhamnetin, glucuronolactone, and 1-Heneicosenol O-β-D-glucopyranoside.
claimThe plant Vernonia amygdalina contains various chemical compounds, including Tricosane, Vernolid, Isorhamnetin, and Luteolin in its flowers, as reported by Habtamu and Melaku (2018).
Medicinal plants and human health: a comprehensive review of ... link.springer.com Nov 5, 2025 4 facts
claimLuteolin controls lipoxygenase pathways, which diminishes leukotriene formation and regulates inflammatory mediators.
measurementLuteolin, derived from Chamaemelum nobile, exhibits preferential inhibition of COX-2 (IC50 = 8.2 μM) compared to COX-1 (IC50 = 45 μM) (Notarte et al. 2023).
claimFlavonoids, such as apigenin and luteolin, inhibit cyclin-dependent kinases, which are required for cell cycle progression.
claimBaicalein from Scutellaria baicalensis and luteolin from other herbs demonstrate anti-neuroinflammatory effects by regulating inflammatory pathways such as NF-κB, MAPK, and JAK-STAT signaling.
Phytochemical and Pharmacological Studies of Traditionally Used ... heraldopenaccess.us 2 facts
claimApigenin, diosmetin, genistein, kaempferol, luteolin, and rosmarinic acid exhibit hypoglycemic action by promoting glucose utilization, enhancing glycogen production in the liver through increased regulatory enzyme expression, and stimulating insulin secretion from the pancreas.
measurementLuteolin found in Vitex negundo Linn. has the chemical formula C15H10O6, a molecular weight of 286.24, and the identifier 5280445.
Wild edible plants for food security, dietary diversity, and nutraceuticals frontiersin.org Nov 27, 2025 1 fact
claimSarcostigma kleinii is used for skin infections, gastric issues, intestinal worms, and rheumatism, and contains protocatechuic acid, chicoric acid, and luteolin, with anaphrodisiac and anthelmintic properties.