Knowledge Tree
IL-10
Also known as: interleukin-10
Facts (12)
Sources
3. The Innate Immune System - Immunopaedia immunopaedia.org.za 3 facts
claimB-1 cells perform immune regulation through the synthesis of IL-10 and participate in the clearance of senescent and apoptotic cells.
claimActivated dendritic cells produce IL-12 family cytokines (IL-12, IL-23, and IL-27) which have Th1-cell polarizing capacity, as well as IL-6, IL-10, and TGF-β which have regulatory T cell polarizing effects.
claimUpon antigen activation, Mucosa-associated invariant T (MAIT) cells produce IFN-gamma, IL-4, IL-5, and IL-10.
Pro-Inflammatory Cytokines Overview | Thermo Fisher Scientific - US thermofisher.com 3 facts
claimThe interleukins IL-10, IL-37, and IL-38 regulate inflammation by suppressing innate and acquired immunity through binding to inhibitory receptors such as IL-18Ra (IL-R5) and IL-1R6.
referenceIL-10 is classified as an anti-inflammatory cytokine, is produced by T cells, B cells, and macrophages, binds to the CDw210 receptor, targets B cells and macrophages, and functions to inhibit cytokine production and mononuclear cell function.
claimRegulatory T cells secrete IL-10, a regulatory cytokine that inhibits excessive T cell responses and balances the immune response.
The Good, The Bad and the Ugly of Inflammation medschool.vanderbilt.edu Feb 10, 2015 2 facts
procedureWu and Kaer restored balance in an animal model by isolating regulatory B lymphocytes from lean mice and transferring them into obese mice, where the cells released IL-10 and improved insulin sensitivity.
claimInnate-like regulatory B lymphocytes secrete interleukin-10 (IL-10), which is an anti-inflammatory cytokine.
How do the indices based on the EAT-Lancet recommendations ... medrxiv.org May 14, 2024 1 fact
claimThe Dietary Inflammatory Index (DII) was developed based on a literature review identifying 45 dietary parameters associated with six inflammatory biomarkers: interleukin (IL)-1β, IL-4, IL-6, IL-10, tumour necrosis factor (TNF)-α, and C-reactive protein.
The Role of Immune Cells in Inflammation jmolpat.com 1 fact
claimMacrophages and other immune cells produce anti-inflammatory cytokines, such as Interleukin-10 (IL-10), to promote the resolution of inflammation and tissue repair.
Homeostatic medicine: a strategy for exploring health and disease link.springer.com Sep 26, 2022 1 fact
claimIn mice susceptible to atherosclerosis, inorganic nitrate intake rescues nitric oxide (NO) homeostasis, which inhibits neutrophil activation and increases IL-10 levels.
Immunity In Depth | Linus Pauling Institute lpi.oregonstate.edu 1 fact
referenceBarrat FJ, Cua DJ, Boonstra A, et al. published 'In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines' in The Journal of Experimental Medicine in 2002 (volume 195, issue 5, pages 603-616), discussing the generation of IL-10-producing regulatory CD4(+) T cells.