concept

Epigallocatechin gallate (EGCG)

Also known as: EGCG, Epigallocatechin gallate (EGCG), Epigallocatechin gallate

Facts (10)

Sources

Medicinal plants and human health: a comprehensive review of ... link.springer.com Springer Nov 5, 2025 7 facts

measurementEpigallocatechin gallate (EGCG) derived from Camellia sinensis demonstrates antifungal efficacy against Candida albicans with a minimum inhibitory concentration (MIC) of 16 μg/mL, reducing ergosterol levels by 80% within 24 hours of administration.

claimEpigallocatechin gallate (EGCG) impacts membrane-associated enzymes, including chitin synthase and β-1,3-glucan synthase, which undermines fungal cell wall integrity.

measurementEpigallocatechin gallate (EGCG) diminishes amyloid-β aggregation by 70–90% at concentrations of 1–10 μM.

claimEpigallocatechin gallate (EGCG) from green tea, curcumin from turmeric, and resveratrol from red grapes inhibit amyloid-β aggregation and facilitate the removal of pre-existing plaques.

referenceZhang Y, Xu Q, Hu J, Zhang F, Yu Y, and Ma L published a systematic review and meta-analysis titled 'Green tea and epigallocatechin gallate (EGCG) for cancer prevention' in the American Journal of Chinese Medicine in 2025.

claimPolyphenolic compounds, specifically resveratrol and EGCG, induce apoptosis in cancer cells by depolarizing the mitochondrial membrane and releasing cytochrome c.

claimGreen tea polyphenols, specifically EGCG, are undergoing rigorous clinical trial testing for cancer prevention and treatment.

Medicinal plants: bioactive compounds, biological activities ... frontiersin.org Frontiers in Immunology 2 facts

claimEpigallocatechin gallate (EGCG) derived from green tea decreases β-lactamase activity in Klebsiella pneumoniae, reinstating susceptibility to β-lactam drugs.

claimCatechin and epigallocatechin gallate inhibit F1Fo-ATPase and lactate dehydrogenase in Streptococcus mutans.

Investigation of nutritional and phytochemical properties of wild ... nature.com Nature Dec 9, 2025 1 fact

claimThe phenolic acids and flavonoids analyzed via UPLC-PDA include P-coumaric acid, Gallic acid, Pro-catechuic acid, Vanillic acid, Rutin, Syringic acid, Caffeic acid, Epicatechin, EGCG, Ferulic acid, Quercetin, and Kaempferol.