concept

ego dissolution

Also known as: ego dissolution scale

Facts (16)

Sources

Psychedelics and Consciousness: Distinctions, Demarcations, and ... ouci.dntb.gov.ua David B Yaden, Matthew W Johnson, Roland R Griffiths, Manoj K Doss, Albert Garcia-Romeu, Sandeep Nayak, Natalie Gukasyan, Brian N Mathur, Frederick S Barrett · Oxford University Press 4 facts

claimThe 5MeO-DMT experience shows high comparability to near-death experiences, particularly in major mystical experiential domains such as ego dissolution and the transcendence of time and space.

referenceMason reported on regional alterations in glutamate and the experience of ego dissolution associated with psilocybin, published in Neuropsychopharmacology (Volume 45, page 2003).

referenceNour validated the Ego-Dissolution Inventory (EDI) in the context of ego-dissolution and psychedelics, published in Frontiers in Human Neuroscience (Volume 10).

claimPath models in the study did not support the mediating role of rumination in the negative link between ayahuasca ceremony effects (indexed via ego-dissolution) and depression, anxiety, and stress scores, although evidence for mediation was found without bootstrapping samples.

The Mechanisms of Psychedelic Visionary Experiences - Frontiers frontiersin.org Frontiers Sep 27, 2017 4 facts

claimDisruption of connections between the parahippocampus and the retrosplenial cortex is directly implicated in the experiences of ego dissolution and the dissolution of self-other boundaries during psychedelic-induced mystical experiences.

claimA. Lebedev, M. Lövdén, G. Rosenthal, A. Feilding, D. Nutt, and R. Carhart-Harris (2015) investigated the neural correlates of ego-dissolution under the influence of psilocybin.

claimDecreased integrity of the Default Mode Network is reflected by decreased functional connectivity between the parahippocampus and retrosplenial cortex, the magnitude of which is strongly correlated with self-report ratings of spiritual experience and ego-dissolution, according to Kometer et al. (2013), Lebedev et al. (2015), Carhart-Harris et al. (2016), and Tagliazucchi et al. (2016).

claimMuthukumaraswamy et al. (2013) and Carhart-Harris et al. (2016) linked decreased connectivity between the parahippocampus and retrosplenial cortex to the experience of “ego-dissolution.”

Psychedelics, Sociality, and Human Evolution frontiersin.org Frontiers 4 facts

referenceE. Tagliazucchi, L. Roseman, M. Kaelen, C. Orban, S. Muthukumaraswamy, and K. Murphy published research in Current Biology in 2016 finding that increased global functional connectivity correlates with LSD-induced ego dissolution.

claimPsilocybin has the capacity to amplify ecstatic and visionary thinking modalities by inducing ego-dissolution, a sense of connectedness, increased elementary and complex imagery, and entity-encounter occurrences.

claimRitual specialists across cultures use collective mythic narratives and coordinated, mixed-modality performances of entrained ritual or dance to provide structure during ego-dissolution and to evoke culturally expected visions.

referenceThe study 'Finding the self by losing the self: neural correlates of ego-dissolution under psilocybin' was published in Human Brain Mapping in 2015, investigating the neural mechanisms of ego-dissolution.

Classification Schemes of Altered States of Consciousness - ORBi orbi.uliege.be ORBi 2 facts

referenceSleight, F.G., Lynn, S.J., Mattson, R.E., and McDonald, C.W. (2023) conducted a construct validation study for a novel ego dissolution scale.

referenceNour et al. (2016) validate the Ego-Dissolution Inventory (EDI) as a tool for measuring ego-dissolution in the context of psychedelic use.

Neuroimaging in psychedelic drug development: past, present, and ... nature.com Nature Sep 27, 2023 1 fact

referenceNour MM, Evans L, Nutt D, Carhart-Harris RL authored 'Ego-dissolution and psychedelics: Validation of the ego-dissolution inventory (EDI)', published in Frontiers in Human Neuroscience in 2016, volume 10, page 269.

Altered State of Consciousness | Springer Nature Link link.springer.com Springer Sep 17, 2025 1 fact

referenceThe study 'Me, myself, bye: Regional alterations in glutamate and the experience of ego dissolution with psilocybin' was published in the journal Neuropsychopharmacology in 2020.