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cell proliferation
Also known as: cellular proliferation
Facts (17)
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Effects of psychedelics on neurogenesis and broader neuroplasticity link.springer.com Dec 19, 2024 8 facts
measurementIn the study by Cho et al. (2008), both 1.25 mg/kg and 20 mg/kg doses of MDMA led to reduced cell proliferation in rat offspring when measured 24 hours post-BrdU labeling, but the higher dose of 20 mg/kg resulted in fewer BrdU-positive cells at 28 days post-BrdU labeling.
claimThe authors included articles that used neuroplasticity biomarkers as an outcome measure, even if those articles did not directly assess neurogenesis or cell proliferation, to account for the limitations of direct neurogenesis measurement in human studies.
accountA study by Liu et al. (2006) found that acute and 5-day chronic exposure to 7.5 mg/kg of phencyclidine (PCP) resulted in minor or no effects on cell proliferation, differentiation, and survival in the dentate gyrus of adult rats compared to saline controls.
referenceA single dose of 5-MeO-DMT stimulates cell proliferation, neuronal survivability, and morphological and functional changes in the adult mouse ventral dentate gyrus, according to a 2018 study by Lima da Cruz et al. published in Frontiers in Molecular Neuroscience.
accountIn the study by Liu et al. (2006), decreases in cell proliferation induced by phencyclidine (PCP) treatments were restored to control levels after one week of abstinence.
measurementNeither LSD (0.5 mg/kg) nor DOI (8 mg/kg) increased cell proliferation in rats under chronic (7 days) or acute treatment regimens, as measured by the BrdU labelling technique.
claimDelta-9-tetrahydrocannabinol (THC) does not affect cell proliferation in the adult mouse dentate gyrus, despite causing strong behavioral disruption.
measurementGarcía-Cabrerizo and García-Fuster (2016) reported that a 60 mg/kg dose of MDMA (administered as 3 × 5 mg/kg over 4 days) had a more significant negative impact on cell proliferation in adult rats (P48-P58) compared to adolescent rats (P27-P37), as measured by ki67 and BrdU labeling.
What are Cytokines? Types & Function - Cleveland Clinic my.clevelandclinic.org Jan 3, 2023 2 facts
claimCytokines signal cell proliferation by instructing a cell to replicate itself, such as telling a white blood cell to produce more white blood cells to fight infection.
claimCytokines are chemical messengers that regulate inflammation in the body by signaling cells on how to behave, including directing cell activation, differentiation, and proliferation.
How to reduce inflammation in the body - MD Anderson Cancer Center mdanderson.org Mar 20, 2026 1 fact
claimChronic inflammation contributes to the initiation, progression, and spread of cancers, including colorectal, lung, stomach, esophageal, breast, and liver cancer, by damaging DNA, promoting cell proliferation, and creating an environment that favors tumor growth.
Wound Healing Phases - StatPearls - NCBI Bookshelf ncbi.nlm.nih.gov 1 fact
claimLaser techniques are being explored as a method to enhance cell proliferation and accelerate wound healing, as evidenced by studies such as Nilforoushzadeh et al. (2019) and Reddy et al. (2019).
Peer-Reviewed Papers - The Levin Lab drmichaellevin.org 1 fact
referenceEndogenous gradients of resting potential instructively pattern embryonic neural tissue through Notch signaling and the regulation of cell proliferation.
Pro-Inflammatory Cytokines Overview | Thermo Fisher Scientific - US thermofisher.com 1 fact
referenceIL-1 is classified as a pro-inflammatory cytokine, is produced by macrophages, B cells, and dendritic cells, binds to the CD121a receptor, targets B cells, NK cells, and T cells, and functions in pyrogenic activity, inflammation, cell proliferation, differentiation, and bone marrow cell proliferation.
Immunity In Depth | Linus Pauling Institute lpi.oregonstate.edu 1 fact
claimRetinoic acid directly or indirectly regulates more than 500 genes, several of which control cellular proliferation and differentiation.
Bioelectricity - The Levin Lab drmichaellevin.org 1 fact
claimIon channels, membrane voltage, and the cell cycle serve as bioelectric controls of cell proliferation, according to a 2009 study by Blackiston, McLaughlin, and Levin published in Cell Cycle.
Bioelectricity | Department of Biology - School of Arts and Sciences as.tufts.edu 1 fact
claimMembrane potential plays a role in the regulation of cell proliferation and differentiation, as reviewed by Sundelacruz, Levin, and Kaplan in 2009.