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cannabinoids
Also known as: cannabinoids, cannabinoid, CB1 agonists, Cannabinoids
Facts (30)
Sources
Industry-Based Misconceptions Regarding Cross-Pollination of ... frontiersin.org Jan 25, 2022 11 facts
claimFemale Cannabis sativa L. plants are industrially exploited for their ability to produce high levels of cannabinoids and terpenes.
referenceSalami et al. (2020) argued for the inclusion of cannabinoids in food and health products in an article titled 'It is our turn to get cannabis high: put cannabinoids in food and health baskets', published in Molecules.
referenceThe two main cannabinoids produced by cannabis are Ξ9-THCA and cannabidiolic acid (CBDA), according to Andre et al. (2016) and Hurgobin et al. (2021).
referenceDesaulniers Brousseau et al. (2021) published research in Frontiers in Plant Science titled 'Cannabinoids and terpenes: how production of photo-protectants can be manipulated to enhance Cannabis sativa L. phytochemistry', which discusses the manipulation of photo-protectants to improve the chemical profile of Cannabis sativa.
measurementCannabis produces 565 secondary metabolites, including 120 cannabinoids, which contribute to its therapeutic potential.
referenceCannabinoids THCA and CBDA are generated via a common pathway utilizing cannabigerolic acid (CBGA), which is acted upon by THCA synthase or CBDA synthase, according to Tahir et al. (2021).
accountA farmer in Montana cultivating hemp on approximately 14,000 acres experienced significant economic loss after purchasing 'feminized' seeds that resulted in over 30% male plants, which exhibited poor cannabinoid yields and inferior growth.
claimClose monitoring of growth conditions is necessary to ensure high cannabinoid yields while maintaining low THC levels by minimizing environmental stressors.
referenceCampbell L. G., Dufresne J., and Sabatinos S. A. published 'Cannabinoid inheritance relies on complex genetic architecture' in Cannabis and Cannabinoid Research in 2020.
claimSelf-pollination in Cannabis sativa L. reduces cannabinoid yields because the plant redirects energy toward seed formation, according to Thomas and ElSohly (2016).
claimTo comply with USDA hemp production guidelines, farmers must select high-quality seeds from certified sources to ensure successful hemp and cannabinoid production.
Effects of psychedelics on neurogenesis and broader neuroplasticity link.springer.com Dec 19, 2024 7 facts
claimThe systematic review categorized psychedelics into five main groups: CB1 agonists, NMDA antagonists, harmala alkaloids, tryptamines, and entactogens.
measurementAmong 18 original articles performing in vitro experiments, 52.6% utilized cannabinoid agonists and 21% utilized tryptamines.
measurementIn the sample of 51 original articles reporting in vivo experiments, the most commonly used psychedelics were cannabinoid agonists (29.4%), NMDA antagonists (27.4%), and tryptamines (17.6%).
claimIn murine models, CB1 agonists (cannabinoids) demonstrate a complex relationship with brain plasticity, where they can enhance plasticity in some protocols but impair neurogenesis in others.
claimMultiple studies have reported that acute or chronic CB1 agonist exposure has a negative or negligible impact on neurogenesis.
measurementStudies examining the effects of CB1 agonists on neurogenesis have utilized a wide range of doses, specifically between 0.75 and 10 mg/kg.
claimCB1 agonists may influence neurogenesis by modulating 5-HT neurons in the dorsal raphe nucleus and ACh neurons in the medial septum, both of which support various stages of neurogenesis.
A critical review of industrial fiber hemp anatomy, agronomic ... bioresources.cnr.ncsu.edu 6 facts
claimAs the hemp plant develops, parts of the plant mature and flower, resulting in higher yields of grain and cannabinoids.
claimHemp inflorescences contain various cannabinoids and secondary metabolites, including THC, non-hallucinogenic CBD, monoterpenoids, and sesquiterpenoids.
claimWhen growing industrial hemp for high grain or cannabinoid yields, the crop should be harvested at full maturity or when 70% of the grains are ripe.
claimTo obtain high-quality bast fiber from industrial hemp, the plant should be harvested before grain and cannabinoids begin to develop.
measurementHemp root contains 0.13% to 0.24% triterpenoids, 0.06% to 0.09% sterols, and 0.001% to 0.004% cannabinoids, according to Jin et al. (2020).
claimHemp grown for grain and cannabinoids is typically shorter than hemp grown for fiber.
Hemp vs. marijuana: Cross-pollination concerns grow | Verisk verisk.com 2 facts
measurementCross-pollination can reduce the cannabinoid content of a marijuana field by about 1 percent.
claimCross-pollination from hemp crops can reportedly reduce the cannabinoid content of a marijuana field by approximately 1 percent.
Medicinal plants and human health: a comprehensive review of ... link.springer.com Nov 5, 2025 2 facts
Advances in Pharmacognosy for Modern Drug Discovery and ... jbph.org 1 fact
referenceA systematic review and meta-analysis evaluated the medical use of cannabinoids.
Published Studies β Johns Hopkins Center for Psychedelic and ... hopkinspsychedelic.org 1 fact
referenceA 2024 review and reanalysis published in Psychological Review examined the unique effects of sedatives, dissociatives, psychedelics, stimulants, and cannabinoids on episodic memory, specifically recollection, familiarity, and metamemory.