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brain volume
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Impact of sleep duration on executive function and brain structure nature.com Mar 3, 2022 11 facts
claimThe study demonstrated a quadratic relationship between sleep duration and brain volume in several brain regions, while other areas showed lower volume only with longer sleep durations.
procedureThe researchers investigated the association between sleep duration and brain volume by comparing individuals who sleep six-to-eight hours against those with other sleep durations (N = 37,553).
procedureMediation analyses were conducted using the Lavaan software package with nonparametric bootstrapping of 1,000 iterations to estimate the directional influence of brain volume on executive function.
measurementThe mediation effect of brain volume on the relationship between sleep duration and executive function resulted in a significant drop in the beta value of a*b = 0.01 (p < 0.001).
referenceA subset of 37,898 individuals from the UK Biobank cohort underwent multi-modal brain imaging to explore the relationship between sleep and brain volume.
claimSleeping between six and eight hours remained predictive of higher brain volume in a regression model that controlled for baseline sleep characteristics, obstructive sleep apnoea traits, smoking, vascular co-morbidity, APOE ε status, body mass index, and socio-economic status.
procedureResearchers used permutation testing to analyze brain volume differences by shuffling datapoints for two different sleep duration groups across brain regions, testing 1000 permuted datasets per region.
claimIn a sub-group of 37,898 individuals who underwent multi-modal brain imaging, researchers explored the relationship between sleep duration and brain volume.
claimSleeping between six and eight hours is significantly associated with higher executive function, and this relationship is partially mediated by brain volume in sleep-related regions.
measurementWhen comparing the six-to-eight hour sleep group to those sleeping less than six hours or more than eight hours, the brain volume difference was driven to a larger extent by the comparison against longer sleep durations, with 47 regions being significantly larger in the six-to-eight hour group.
measurementVolume in 56 brain regions significantly predicted executive function, while volume in 46 brain regions showed a significant quadratic relationship with sleep duration.
5.1 Physical Health and Growth in Early Childhood - OpenStax openstax.org Oct 16, 2024 1 fact
claimThe amount of stimulation a child receives from an early age significantly affects brain structure, weight, and volume according to Gilmore et al. (2018), Lawson (2013), and Ziegler et al. (2020).
Is There a Male Brain and a Female Brain? | Child & Family Blog childandfamilyblog.com 1 fact
measurementAt birth, the total difference in brain volume between boys and girls is 6%, which increases to 11% in adulthood.
The battle of the sexes: Whose brain comes out on top? pennneuroknow.com Dec 23, 2025 1 fact
measurementMen's brains are, on average, 11% larger in volume than women's brains.