Clearance of senescent cells (SCs) and decreasing the senescence-associated secretory phenotype (SASP) benefit organ repair and disease treatment, but senolytics often have poor cell selectivity that may damage normal tissue, and SASP inhibitors targeting specific secretory factors have limited therapeutic effects on multiple factors-mediated diseases.

Authors

• Person: Not available Organization: Nature
  Cellular rejuvenation: molecular mechanisms and potential ... - Nature

Sources

• Cellular rejuvenation: molecular mechanisms and potential ... - Nature www.nature.com Nature via serper

Referenced by nodes (3)

• senolytics concept
• senescent cells concept
• senescence-associated secretory phenotype concept