The two-cell, two-gonadotropin hypothesis of regulation of estrogen synthesis in the human ovary states that LH stimulates theca cells to produce androstenedione, which is then transported to granulosa cells where it is aromatized to estrone and converted to estradiol by 17-β-hydroxysteroid dehydrogenase type I.

Authors

• Person: Feingold KR, Adler RA, Ahmed SF Organization: National Center for Biotechnology Information
  The Normal Menstrual Cycle and the Control of Ovulation - NCBI - NIH

Sources

• The Normal Menstrual Cycle and the Control of Ovulation - NCBI - NIH www.ncbi.nlm.nih.gov Feingold KR, Adler RA, Ahmed SF · National Center for Biotechnology Information via serper

Referenced by nodes (4)

• luteinizing hormone (LH) concept
• estradiol concept
• granulosa cells concept
• estrone concept