In the central nervous system, heterochronic parabiosis experiments showed that young mice exposed to an old systemic environment or plasma from old mice exhibit diminished synaptic plasticity and impaired contextual fear conditioning, spatial learning, and memory, while systemic infusion of young blood plasma reverses these effects.

Authors

• Person: Not available Organization: Nature
  Cellular rejuvenation: molecular mechanisms and potential ... - Nature

Sources

• Cellular rejuvenation: molecular mechanisms and potential ... - Nature www.nature.com Nature via serper

Referenced by nodes (2)

• spatial learning concept
• Heterochronic parabiosis concept