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Positive emotional experiences and profound quiescence of meditative practices result from a deafferentation of limbic stimulation from the peripheral parasympathetic system, combined with reverberating parietal lobule connections with Prefrontal Cortex (PFC) circuits that result in stimulation of both divisions of the Autonomic Nervous System and enhanced connections of the sensory association areas with the inferior parietal lobe, a key Default Mode Network (DMN) area.

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