When a target cell exhibits decreased expression of MHC-I, the inhibitory signal from the Natural Killer (NK) cell's killer inhibitory receptors (KIRs) decreases, shifting the signal balance toward activation and initiating apoptosis.

Authors

• Person: Not available Organization: Immunopaedia
  3. The Innate Immune System - Immunopaedia

Sources

• 3. The Innate Immune System - Immunopaedia www.immunopaedia.org.za Immunopaedia via serper

Referenced by nodes (2)

• apoptosis concept
• NK cells concept